RUNDC3A and TFPT

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		RUNDC3A	TFPT
Gene Name		RUN domain containing 3A	TCF3 (E2A) fusion partner (in childhood Leukemia)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Actin Filament Ino80 Complex Nuclear Membrane
	Molecular Function	Small GTPase Regulator Activity Guanylate Cyclase Activator Activity Peptide Hormone Receptor Binding	DNA Binding Protein Binding Protein Kinase Binding Protein Heterodimerization Activity
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of Guanylate Cyclase Activity	DNA Repair DNA Recombination Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Apoptotic Process Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		22 interactors: AP1M1 AP2M1 ARMC7 CCNL2 DDX6 EIF3E FAM161A GEM GFI1B MAGEB4 MAGOHB MRPL15 MYO15B RAP1A RAP2A RAP2B SDCBP SYT17 TBRG1 TFPT ZNF417 ZNF587	23 interactors: APP C4orf46 CCDC67 CDCA7L DYDC1 EAF1 EAF2 ELL HAUS1 KRT19 LMO2 NOL3 PAWR PIM1 RALBP1 RPGRIP1 RUNDC3A SDCCAG3 STK3 TCF3 TFIP11 TPM1 TPM3
Entrez ID		10900	29844
HPRD ID		16106	10266
Ensembl ID		ENSG00000108309	ENSG00000105619
Uniprot IDs		Q59EK9	P0C1Z6
PDB IDs
Enriched GO Terms of Interacting Partners?		Rap Protein Signal Transduction Ras Protein Signal Transduction Positive Regulation Of Protein Autophosphorylation Small GTPase Mediated Signal Transduction Regulation Of Defense Response To Virus By Virus Regulation Of Protein Autophosphorylation Gene Expression	Positive Regulation Of Metabolic Process Apoptotic Process RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Programmed Cell Death Regulation Of Metabolic Process Cell Death Death Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Embryo Development Regulation Of Transcription, DNA-templated Actin-myosin Filament Sliding Muscle Filament Sliding Regulation Of Nucleic Acid-templated Transcription Embryonic Hemopoiesis Regulation Of RNA Biosynthetic Process Cell Differentiation Involved In Embryonic Placenta Development Regulation Of RNA Metabolic Process Regulation Of Catalytic Activity Organelle Assembly Actin-mediated Cell Contraction Cellular Component Assembly In Utero Embryonic Development Spliceosomal Complex Disassembly Response To Injury Involved In Regulation Of Muscle Adaptation Positive Regulation Of Heart Rate By Epinephrine Sarcomere Organization Regulation Of B Cell Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Actin Filament-based Movement Positive Regulation Of Catalytic Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Cell Cycle Actin Filament-based Process Myofibril Assembly Transcription, DNA-templated Organ Development Muscle Cell Differentiation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Collateral Sprouting In Absence Of Injury Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Tissue Development Protein Stabilization Developmental Process
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