RUNDC3A and MRPL15

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		RUNDC3A	MRPL15
Description		RUN domain containing 3A	mitochondrial ribosomal protein L15
Image		No pdb structure
GO Annotations	Cellular Component		Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Ribosome Large Ribosomal Subunit Ribonucleoprotein Complex
	Molecular Function	Protein Binding GTPase Regulator Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Small GTPase-mediated Signal Transduction Positive Regulation Of CGMP-mediated Signaling	Translation Mitochondrial Translation Cellular Response To Leukemia Inhibitory Factor
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS			LDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		37 interacting genes: AP1M1 AP2M1 ARMC7 CCNL2 DDX6 EIF3E ENKD1 FAM161A GEM GFI1B HTR6 LNX1 MAGEB4 MAGOHB MBD3L2 MRPL15 MYO15B PRPF31 RAP1A RAP2A RAP2B SDCBP SHANK3 SYT17 TBRG1 TEAD4 TFPT TSC1 TSGA10IP TSHR UBTFL1 USP2 ZNF250 ZNF417 ZNF587 ZNF821 ZNF835	5 interacting genes: CCNDBP1 RHOU RUNDC3A SNRPA U2AF2
Entrez ID		10900	29088
HPRD ID		16106	14742
Ensembl ID		ENSG00000108309	ENSG00000137547
Uniprot IDs		Q59EK9	Q9P015
PDB IDs			3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OI6 7OI7 7OI8 7OI9 7OIA 7OIB 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8PK0 8QSJ 8QU1 8QU5 8RRI 8XT0 8XT1 8XT2 8XT3
Enriched GO Terms of Interacting Partners?		Rap Protein Signal Transduction GDP Binding	MRNA Splicing, Via Spliceosome Spliceosomal Complex U1 SnRNA Binding Spliceosomal SnRNP Complex RNA Splicing, Via Transesterification Reactions U1 SnRNP Binding Positive Regulation Of CGMP-mediated Signaling Small GTPase-mediated Signal Transduction Commitment Complex U2AF Complex Poly-pyrimidine Tract Binding Pre-mRNA 3'-splice Site Binding Positive Regulation Of Focal Adhesion Disassembly RNA Splicing Regulation Of CGMP-mediated Signaling Prp19 Complex C2H2 Zinc Finger Domain Binding U2-type Prespliceosome U1 SnRNP MRNA Processing Negative Regulation Of MRNA Splicing, Via Spliceosome
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