RUNDC3A and CCNL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		RUNDC3A	CCNL2
Description		RUN domain containing 3A	cyclin L2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Protein Binding GTPase Regulator Activity	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process	Small GTPase-mediated Signal Transduction Positive Regulation Of CGMP-mediated Signaling	Regulation Of Transcription By RNA Polymerase II Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of Centrosome Cycle Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		37 interacting genes: AP1M1 AP2M1 ARMC7 CCNL2 DDX6 EIF3E ENKD1 FAM161A GEM GFI1B HTR6 LNX1 MAGEB4 MAGOHB MBD3L2 MRPL15 MYO15B PRPF31 RAP1A RAP2A RAP2B SDCBP SHANK3 SYT17 TBRG1 TEAD4 TFPT TSC1 TSGA10IP TSHR UBTFL1 USP2 ZNF250 ZNF417 ZNF587 ZNF821 ZNF835	15 interacting genes: CDK11B DYRK1A EMD FAM90A1 KRTAP12-2 MAGEB2 MDFI PIH1D2 POLR2A RUNDC3A SRSF2 SRSF7 TRIM41 USP20 ZBTB7B
Entrez ID		10900	81669
HPRD ID		16106	10815
Ensembl ID		ENSG00000108309	ENSG00000221978
Uniprot IDs		Q59EK9	Q96S94
PDB IDs
Enriched GO Terms of Interacting Partners?		Rap Protein Signal Transduction GDP Binding	Regulation Of RNA Splicing Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Positive Regulation Of RNA Splicing Negative Regulation Of RNA Metabolic Process Histone H3T45 Kinase Activity TMEM240-body Negative Regulation Of NK T Cell Proliferation
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