PNMA2 and CBX8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PNMA2	CBX8
Gene Name		paraneoplastic Ma antigen 2	chromobox homolog 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus	Nuclear Chromatin Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Protein Binding	Single-stranded RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Methylated Histone Binding
	Biological Process	Positive Regulation Of Apoptotic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Histone Ubiquitination
Pathways			Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: BYSL CBX8 CCDC33 ENKD1 FAM161A LRR1 MORF4L2 PPIG PRPF31 PSMA1 RNF8 RPL9 RTP5 SCNM1 SDCBP TOP3B TTLL10 ZNF417 ZNF587	42 interactors: BMI1 CALCOCO2 CCDC136 CCDC57 EEF1G FSD2 GOLGA2 GPRASP2 HAP1 HIST3H3 HMBOX1 IKZF1 KAT5 KAT7 KCTD9 KIFC3 KRT40 LZTS2 MID2 MLLT1 MLLT3 MTUS2 PAXIP1 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 PHC2 PNMA2 RING1 RNF2 RPGRIP1 SETDB1 SOX5 TFCP2 TRAF2 TSGA10 UNC119 USP11 USP7 ZBTB14
Entrez ID		10687	57332
HPRD ID		04915	13006
Ensembl ID		ENSG00000240694
Uniprot IDs		Q5U5Z3 Q9UL42	Q9HC52
PDB IDs			3I91
Enriched GO Terms of Interacting Partners?		Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Gene Expression Histone Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Metabolic Process RNA Splicing Histone H2A K63-linked Ubiquitination Positive Regulation Of Extracellular Vesicular Exosome Assembly Chromosome Organization	Transcription, DNA-templated RNA Biosynthetic Process Histone Modification Chromatin Modification Chromosome Organization Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone Ubiquitination Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Biosynthetic Process Histone H2A Monoubiquitination Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Histone H2A Ubiquitination Peptidyl-lysine Modification Regulation Of Metabolic Process Histone Monoubiquitination Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein Ubiquitination Organelle Organization Histone Acetylation Protein Modification By Small Protein Conjugation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Monoubiquitination Anterior/posterior Pattern Specification Protein Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Segment Specification Cellular Protein Modification Process Cellular Response To Reactive Oxygen Species
Tagcloud ?			aims approaches beings blotting causes chromobox colon conclude cultured express facilitating hct116 homolog igf1 igf1r knockdown leading line overexpression pathogenesis proliferation promote promoting real reports rt silencing unclear western
Tagcloud (Difference) ?			aims approaches beings blotting causes chromobox colon conclude cultured express facilitating hct116 homolog igf1 igf1r knockdown leading line overexpression pathogenesis proliferation promote promoting real reports rt silencing unclear western
Tagcloud (Intersection) ?