PNMA2 and PPIG

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PNMA2	PPIG
Description		PNMA family member 2	peptidylprolyl isomerase G
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GO Annotations	Cellular Component	Nucleus Nucleolus	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Speck
	Molecular Function	Protein Binding	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Isomerase Activity
	Biological Process	Positive Regulation Of Apoptotic Process	Protein Folding RNA Splicing
Pathways			mRNA Splicing - Major Pathway SARS-CoV-1 activates/modulates innate immune responses
Drugs			Proline
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		32 interacting genes: BYSL CBX8 CCDC33 CDC37 CNNM3 ENKD1 FAM161A GPATCH2L HAPLN2 INO80B LRR1 MISP MORF4L2 NTAQ1 PPIG PRPF31 PSMA1 RNF6 RNF8 RPL9 RSPH1 RTP5 SCNM1 SDCBP THAP7 TOP3B TTLL10 ZNF408 ZNF417 ZNF587 ZNF669 ZNF688	26 interacting genes: BEND7 CACNA1A CEP70 CLK1 DAB1 DACH1 FHL3 KCTD6 LGALS3 PCBP1 PNMA2 PNN POLR2A PPCDC PRPF38A PRPF40A RNF10 SLU7 SMN1 SMN2 SP1 TFCP2 THAP1 TRIM54 YWHAG ZCCHC10
Entrez ID		10687	9360
HPRD ID		04915	12083
Ensembl ID		ENSG00000240694	ENSG00000138398
Uniprot IDs		Q5U5Z3 Q9UL42	Q13427
PDB IDs		8UYO	2GW2 2WFI 2WFJ 5YZG
Enriched GO Terms of Interacting Partners?		Nucleus	MRNA Metabolic Process RNA Splicing RNA Splicing, Via Transesterification Reactions RNA Metabolic Process MRNA Processing DNA-templated Transcription Termination Z Disc Nucleus Nucleic Acid Metabolic Process SMN Complex Gemini Of Cajal Bodies Spliceosomal Complex Nucleobase-containing Compound Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Biosynthetic Process Cytoplasmic Ribonucleoprotein Granule SMN-Sm Protein Complex RNA Binding Nuclear Speck Transcription Cis-regulatory Region Binding DNA Binding Nucleoplasm Protein Binding Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of Hydrogen Sulfide Biosynthetic Process Cellular Response To Wortmannin Second Spliceosomal Transesterification Activity Phosphopantothenoylcysteine Decarboxylase Activity Phosphopantothenoylcysteine Decarboxylase Complex
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