FARS2 and TFCP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FARS2	TFCP2
Gene Name		phenylalanyl-tRNA synthetase 2, mitochondrial	transcription factor CP2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix	Cellular_component Nucleus
	Molecular Function	TRNA Binding Magnesium Ion Binding Phenylalanine-tRNA Ligase Activity ATP Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation TRNA Processing Gene Expression	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		tRNA Aminoacylation Mitochondrial tRNA aminoacylation
Drugs		L-Phenylalanine
Diseases
GWAS		Obesity (early onset extreme) ( 23563609)
Protein-Protein Interactions		23 interactors: ADAMTSL4 AGTRAP APPL1 CALCOCO2 CMTM5 HMBOX1 IKZF3 KRT13 KRT31 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-9 MID2 MKRN3 NOTCH2NL RCBTB2 STX11 TADA2A TFCP2 TRIM27 TRIM54	62 interactors: ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CASP8 CBX8 CCDC94 CDC73 COIL DNAJC27 DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM64A FANCL FARS2 FBXL18 GPANK1 HDAC1 HDAC2 IRAK1BP1 KIAA1598 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NFE4 NOM1 NPEPL1 PHF1 PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 SDCBP SIN3A STMN2 SUMO1 TCEA2 TDRD1 TRAPPC12 TSPAN12 UBP1 YY1 ZCCHC10 ZCCHC12
Entrez ID		10667	7024
HPRD ID		09946	01790
Ensembl ID		ENSG00000145982	ENSG00000135457
Uniprot IDs		O95363	Q12800
PDB IDs		3CMQ 3HFV 3TEG 3TUP
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell	Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Cellular Response To Stress Chromatin Modification Cellular Protein Metabolic Process Histone Modification Chromatin Organization Negative Regulation Of Gene Expression Cell Cycle Negative Regulation Of Cellular Metabolic Process Protein Metabolic Process Histone Deacetylation Regulation Of Gene Expression Chromosome Organization Regulation Of Metabolic Process Protein Deacetylation TRIF-dependent Toll-like Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Innate Immune Response Activation Of Innate Immune Response Metabolic Process Negative Regulation Of Transcription, DNA-templated Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Stimulus Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Regulation Of Organelle Organization Negative Regulation Of Gene Expression, Epigenetic Cellular Protein Modification Process Negative Regulation Of RNA Biosynthetic Process Peptidyl-amino Acid Modification Toll-like Receptor 4 Signaling Pathway Anatomical Structure Development Anatomical Structure Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated
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