FARS2 and TADA2A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FARS2	TADA2A
Gene Name		phenylalanyl-tRNA synthetase 2, mitochondrial	transcriptional adaptor 2A
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Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix	PCAF Complex Nucleus Chromosome
	Molecular Function	TRNA Binding Magnesium Ion Binding Phenylalanine-tRNA Ligase Activity ATP Binding	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity Histone Acetyltransferase Activity Zinc Ion Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation TRNA Processing Gene Expression	Chromatin Organization Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Histone H3 Acetylation
Pathways		tRNA Aminoacylation Mitochondrial tRNA aminoacylation	Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs		L-Phenylalanine
Diseases
GWAS		Obesity (early onset extreme) ( 23563609)	Ovarian cancer ( 23535730)
Protein-Protein Interactions		23 interactors: ADAMTSL4 AGTRAP APPL1 CALCOCO2 CMTM5 HMBOX1 IKZF3 KRT13 KRT31 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-9 MID2 MKRN3 NOTCH2NL RCBTB2 STX11 TADA2A TFCP2 TRIM27 TRIM54	34 interactors: ARNT2 C1orf109 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FAM127C FARS2 FBF1 GPSM3 HGS KAT2A KLC4 KLHL38 KPNA2 LOC149950 MAGOH MCPH1 MFAP1 MTX2 MYC NR3C1 PPP1R16B PRKAB2 PRPF31 SF3A3 TADA3 TCF3 TEKT4 TTC23 TTC9C ZFYVE26 ZNF564
Entrez ID		10667	6871
HPRD ID		09946	03784
Ensembl ID		ENSG00000145982	ENSG00000108264
Uniprot IDs		O95363	O75478
PDB IDs		3CMQ 3HFV 3TEG 3TUP	1X41
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell	Histone H3 Acetylation Gene Expression RNA Metabolic Process Posttranscriptional Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Histone Acetylation Heterocycle Metabolic Process Internal Peptidyl-lysine Acetylation Cellular Aromatic Compound Metabolic Process Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Protein Stability Cellular Nitrogen Compound Metabolic Process Chromatin Modification Transcription, DNA-templated Cytoplasmic Transport RNA Biosynthetic Process Chromatin Organization Regulation Of Gluconeogenesis Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Glucocorticoid Mediated Signaling Pathway Exocyst Assembly Cellular Macromolecule Biosynthetic Process Establishment Of Localization In Cell Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Histone H4 Acetylation Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Organelle Organization Positive Regulation Of Cell Proliferation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Peptidyl-serine Dephosphorylation Fibroblast Apoptotic Process Protein Localization To Organelle Transcription From RNA Polymerase II Promoter Peptidyl-lysine Modification Intracellular Steroid Hormone Receptor Signaling Pathway Nucleocytoplasmic Transport Nuclear Transport Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Glucocorticoid Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Regulation Of Chromosome Condensation Regulation Of Metabolic Process Cellular Protein Localization Cellular Localization
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