FARS2 and RCBTB2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FARS2	RCBTB2
Gene Name		phenylalanyl-tRNA synthetase 2, mitochondrial	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix
	Molecular Function	TRNA Binding Magnesium Ion Binding Phenylalanine-tRNA Ligase Activity ATP Binding	Ran Guanyl-nucleotide Exchange Factor Activity
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation TRNA Processing Gene Expression	Positive Regulation Of Ran GTPase Activity
Pathways		tRNA Aminoacylation Mitochondrial tRNA aminoacylation
Drugs		L-Phenylalanine
Diseases
GWAS		Obesity (early onset extreme) ( 23563609)
Protein-Protein Interactions		23 interactors: ADAMTSL4 AGTRAP APPL1 CALCOCO2 CMTM5 HMBOX1 IKZF3 KRT13 KRT31 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-9 MID2 MKRN3 NOTCH2NL RCBTB2 STX11 TADA2A TFCP2 TRIM27 TRIM54	6 interactors: COPS4 CUL3 FARS2 PDE4B UBE2E3 UBE2I
Entrez ID		10667	1102
HPRD ID		09946	04631
Ensembl ID		ENSG00000145982	ENSG00000136161
Uniprot IDs		O95363	B4DWG0 O95199
PDB IDs		3CMQ 3HFV 3TEG 3TUP
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell	Positive Regulation Of SUMO Transferase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Negative Regulation Of Relaxation Of Cardiac Muscle Trophectodermal Cellular Morphogenesis Protein Polyubiquitination Cellular Protein Metabolic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation Chromosome Segregation Phenylalanyl-tRNA Aminoacylation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Relaxation Of Cardiac Muscle Proteasomal Protein Catabolic Process Positive Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Relaxation Of Muscle Cullin Deneddylation Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Mitotic Nuclear Division Protein Deneddylation Embryonic Cleavage Protein Metabolic Process Neutrophil Homeostasis CAMP Catabolic Process Stress Fiber Assembly Positive Regulation Of Chromosome Segregation Cellular Protein Modification Process Cellular Response To Epinephrine Stimulus Cell Division Response To Epinephrine Cyclic Nucleotide Catabolic Process COPII Vesicle Coating Regulation Of Voltage-gated Calcium Channel Activity COPII-coated Vesicle Budding Protein K11-linked Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Purine Ribonucleotide Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Modification-dependent Protein Catabolic Process Protein Sumoylation Trophectodermal Cell Differentiation Cellular Response To Catecholamine Stimulus Mitotic Metaphase Plate Congression Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Vesicle Targeting, To, From Or Within Golgi Cellular Protein Catabolic Process Metaphase Plate Congression
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