BAIAP2L1

Gene Name		BAI1-associated protein 2-like 1
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Proline-rich Region Binding
	Biological Process	Plasma Membrane Organization Response To Bacterium Positive Regulation Of Actin Filament Polymerization Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Actin Cytoskeleton Reorganization
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Prostate cancer (gene x gene interaction) ( 22219177) Sex hormone-binding globulin levels ( 22829776)
Protein-protein Interactions		6 interactors: FASLG KHDRBS1 MDM2 TP53 WAS YWHAG
Entrez ID		55971
HPRD ID		11270
Ensembl ID		ENSG00000006453
Uniprot IDs		Q9UHR4
PDB IDs		2KXC 2LNH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Intracellular Transport Regulation Of Intracellular Transport Mitotic Cell Cycle Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Transport Mitotic Cell Cycle Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Necroptotic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Apoptotic Process Programmed Cell Death Regulation Of Signal Transduction By P53 Class Mediator Programmed Necrotic Cell Death Regulation Of Cellular Localization Cell Cycle Process Necrotic Cell Death Cell Death Death Regulation Of Catalytic Activity Apoptotic Signaling Pathway Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of RNA Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Cellular Response To UV Positive Regulation Of Mitochondrion Organization Signal Transduction Involved In Cell Cycle Checkpoint Positive Regulation Of Neuron Apoptotic Process Response To Antibiotic Positive Regulation Of Organelle Organization Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Immune Response Regulation Of Signal Transduction Signal Transduction Negative Regulation Of Cell Cycle Mitotic G1 DNA Damage Checkpoint Negative Regulation Of Gene Expression Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Negative Regulation Of Biosynthetic Process Positive Regulation Of Neuron Death Cell Cycle
Tagcloud ?		amphiphysin bai1 bar bin cdkn2a ch5183284 constitutive debio deltabar dimerization discovered f3 fgfr fgfr3 fibroblast fusion harboring oncogenic rat rat2 rb1 rearrangements rvs screens signature suppressive transfectant transforming tumorigenic