MYO1C and BAZ1B

Number of citations of the paper that reports this interaction (PMID 16514417)
32

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		MYO1C	BAZ1B
Gene Name		myosin IC	bromodomain adjacent to zinc finger domain, 1B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Ruffle Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Mitochondrion Cytosol Plasma Membrane Microvillus Brush Border Basal Plasma Membrane Membrane Cytoplasmic Membrane-bounded Vesicle Lateral Plasma Membrane Unconventional Myosin Complex Filamentous Actin Membrane Raft Myosin I Complex Stereocilium Membrane Extracellular Vesicular Exosome	Condensed Chromosome Pericentric Heterochromatin Nuclear Replication Fork
	Molecular Function	Motor Activity Actin Binding Receptor Binding Protein Binding Calmodulin Binding ATP Binding Protein C-terminus Binding Ral GTPase Binding Actin-dependent ATPase Activity	Chromatin Binding Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Histone Kinase Activity Lysine-acetylated Histone Binding Vitamin D Receptor Activator Activity
	Biological Process	Protein Targeting Protein Targeting To Membrane Positive Regulation Of Cell Migration Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response MRNA Transport Membrane Organization Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Tight Junction Assembly	Heart Morphogenesis Double-strand Break Repair Chromatin Assembly Or Disassembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Histone Phosphorylation Peptidyl-tyrosine Phosphorylation Chromatin-mediated Maintenance Of Transcription Positive Regulation Of Receptor Activity
Pathways		Translocation of GLUT4 to the plasma membrane Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS			Hypertriglyceridemia ( 23505323) Protein C levels ( 20802025) Triglycerides ( 20864672) Urate levels ( 23263486)
Protein-Protein Interactions		4 interactors: BAZ1B CBL KHDRBS1 RRN3	15 interactors: CDT1 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE MAPK14 MAPK3 MAPK9 MYO1C NR4A2 PCNA SMARCA1 SMARCA5 SMARCC2 SMARCE1
Entrez ID		4641	9031
HPRD ID		09411	10416
Ensembl ID		ENSG00000197879	ENSG00000009954
Uniprot IDs		F5H6E2 O00159	Q9UIG0
PDB IDs			1F62
Enriched GO Terms of Interacting Partners?		Regulation Of Signal Transduction Regulation Of Signaling Positive Regulation Of RNA Export From Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Nucleolus Organization Cytoplasm Organization Regulation Of RNA Metabolic Process Chromatin-mediated Maintenance Of Transcription Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Export From Nucleus Positive Regulation Of Translational Initiation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Gene Expression, Epigenetic Transcription, DNA-templated Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of DNA-templated Transcription, Initiation RNA Biosynthetic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Transcription Initiation From RNA Polymerase I Promoter Positive Regulation Of Cellular Metabolic Process Cell Proliferation Transcription From RNA Polymerase I Promoter Positive Regulation Of Transport Positive Regulation Of Receptor-mediated Endocytosis Histone Phosphorylation Positive Regulation Of Receptor Activity Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death RNA Metabolic Process Negative Regulation Of Cell Death Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Signal Transduction Regulation Of Translational Initiation Cellular Macromolecule Biosynthetic Process Positive Regulation Of Translation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Macromolecule Biosynthetic Process Regulation Of ERBB Signaling Pathway	Nucleosome Organization ATP-dependent Chromatin Remodeling Chromatin Assembly Or Disassembly Chromosome Organization Chromatin Remodeling Chromatin Organization Chromatin Silencing At RDNA Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleosome Assembly Chromatin Silencing Chromatin Assembly Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organelle Organization Protein-DNA Complex Assembly DNA Packaging Regulation Of Transcription From RNA Polymerase II Promoter Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Gene Expression, Epigenetic DNA Replication-dependent Nucleosome Assembly Toll-like Receptor 4 Signaling Pathway DNA Conformation Change Chromatin Modification DNA Metabolic Process DNA Methylation On Cytosine Gene Silencing Nucleosome Disassembly Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Nitrogen Compound Metabolic Process Response To Stress Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Nucleobase-containing Compound Metabolic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Transcription, DNA-templated Activation Of Innate Immune Response
Tagcloud ?		actin attenuates blocked cargo cooperatively cytoskeletal deletion diminished dominant essential ikappab ikk intact interaction irs lacking modulator motor necrosis nemo network phosphorylates precise requires ruffles ser307 silencing tnf trafficking	ac accessible architecture attenuates clarify cytoprotective foci gammah2ax h2ax h3k56 h3k9 hubs integrated ints3 irradiation isoform mark matrix mount prevents proteomic respond runx runx2 ruvbl2 scaffolding subnuclear supported uv
Tagcloud (Difference) ?		actin blocked cargo cooperatively cytoskeletal deletion diminished dominant essential ikappab ikk intact interaction irs lacking modulator motor necrosis nemo network phosphorylates precise requires ruffles ser307 silencing tnf trafficking	ac accessible architecture clarify cytoprotective foci gammah2ax h2ax h3k56 h3k9 hubs integrated ints3 irradiation isoform mark matrix mount prevents proteomic respond runx runx2 ruvbl2 scaffolding subnuclear supported uv
Tagcloud (Intersection) ?		attenuates