PAIP1 and RND1

Number of citations of the paper that reports this interaction (PubMedID 30797814)
0

Data Source:
BioGRID (two hybrid)

		PAIP1	RND1
Description		poly(A) binding protein interacting protein 1	Rho family GTPase 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol MCRD-mediated MRNA Stability Complex	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Actin Cytoskeleton Membrane
	Molecular Function	RNA Binding Protein Binding Translation Activator Activity	Nucleotide Binding GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Translational Initiation Regulation Of Translation Regulation Of Translational Initiation Host-mediated Activation Of Viral Process MRNA Stabilization CRD-mediated MRNA Stabilization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Cytoplasmic Translation	Actin Filament Organization Negative Regulation Of Cell Adhesion Signal Transduction Small GTPase-mediated Signal Transduction Neuron Remodeling Regulation Of Actin Cytoskeleton Organization
Pathways		Deadenylation of mRNA Deadenylation of mRNA M-decay: degradation of maternal mRNAs by maternally stored factors Z-decay: degradation of maternal mRNAs by zygotically expressed factors	SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse RND1 GTPase cycle
Drugs
Diseases
GWAS		Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Bipolar disorder ( 21926972)
Interacting Genes		10 interacting genes: EIF3A EIF3B EIF4A1 MYB OGT PABPC1 RND1 TMEM132D UBR5 WWP2	21 interacting genes: ARFIP2 CCNI COPS2 CREB3L2 EEF1A1 FRS2 FRS3 GPX8 GRB7 ID3 MYH7 MYOM3 MYZAP NEDD1 PAIP1 PDE6D PLXNA1 PLXNB1 PLXNB2 UBXN11 ZNF212
Entrez ID		10605	27289
HPRD ID		05539	12357
Ensembl ID		ENSG00000172239	ENSG00000172602
Uniprot IDs		Q9H074	Q92730
PDB IDs		1JH4 3NTW 3RK6 6YXJ	2CLS 2REX 3Q3J
Enriched GO Terms of Interacting Partners?		Cytoplasmic Translational Initiation Translation Initiation Factor Activity Viral Translational Termination-reinitiation Eukaryotic Translation Initiation Factor 3 Complex, EIF3m Translational Initiation Cytoplasmic Stress Granule IRES-dependent Viral Translational Initiation Translation Formation Of Cytoplasmic Translation Initiation Complex Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 48S Preinitiation Complex Eukaryotic 43S Preinitiation Complex Cytosol MRNA Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Macromolecule Biosynthetic Process RNA Binding Positive Regulation Of Hepatic Stellate Cell Proliferation Eukaryotic Translation Initiation Factor 3 Complex, EIF3e Heterochromatin Boundary Formation Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Testosterone Secretion Regulation Of Translational Initiation Regulation Of Translation Protein O-acetylglucosaminyltransferase Activity Translation Reinitiation Multi-eIF Complex Cytoplasm Protein Quality Control By The Ubiquitin-proteasome System Positive Regulation Of RNA Metabolic Process Cytoplasm Protein Quality Control Vitamin D Receptor Signaling Pathway	Semaphorin Receptor Complex Semaphorin Receptor Activity Semaphorin-plexin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Synapse Assembly
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