ARFGEF1 and DPY30

Number of citations of the paper that reports this interaction (PMID 20668708)
3

Data Source:
BioGRID (pull down)

		ARFGEF1	DPY30
Gene Name		ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)	dpy-30 homolog (C. elegans)
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Nuclear Matrix Small Nuclear Ribonucleoprotein Complex Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Golgi Apparatus Trans-Golgi Network Histone Methyltransferase Complex Set1C/COMPASS Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding ARF GTPase Activator Activity Myosin Binding Protein Kinase A Regulatory Subunit Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Exocytosis Golgi Organization Endomembrane System Organization Protein Transport Vesicle-mediated Transport Negative Regulation Of Actin Filament Polymerization Regulation Of ARF Protein Signal Transduction Negative Regulation Of Rho GTPase Activity Positive Regulation Of GTPase Activity Positive Regulation Of Protein Glycosylation In Golgi Positive Regulation Of Wound Healing Regulation Of Establishment Of Cell Polarity	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Endosomal Transport Histone H3-K4 Methylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ARFGEF2 DPY30 FKBP2 MYO9B	10 interactors: ARFGEF1 ASH2L CHMP2B DYDC1 GTF2I HIST3H3 PRPF3 PSMD14 SETD1A TMCC2
Entrez ID		10565	84661
HPRD ID		09163	17434
Ensembl ID		ENSG00000066777
Uniprot IDs		Q9Y6D6	B4DIS3 Q9C005
PDB IDs		3LTL	3G36
Enriched GO Terms of Interacting Partners?			Histone H3-K4 Methylation Chromosome Organization Positive Regulation Of Protein Glycosylation In Golgi Histone Lysine Methylation Peptidyl-lysine Methylation Transition Between Slow And Fast Fiber Histone Methylation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Positive Regulation Of Protein Glycosylation Cellular Aromatic Compound Metabolic Process Protein Methylation Organelle Organization Cellular Nitrogen Compound Metabolic Process Viral Budding Via Host ESCRT Complex Gene Expression Nitrogen Compound Metabolic Process Regulation Of Skeletal Muscle Adaptation Regulation Of Mitotic Spindle Assembly Negative Regulation Of Cytosolic Calcium Ion Concentration Viral Budding Peptidyl-lysine Modification Regulation Of Spindle Assembly Regulation Of Protein Glycosylation Regulation Of Mitotic Spindle Organization Negative Regulation Of Rho GTPase Activity Spliceosomal Tri-snRNP Complex Assembly Positive Regulation Of Glycoprotein Biosynthetic Process Regulation Of Protein Complex Assembly Positive Regulation Of Glycoprotein Metabolic Process Protein K63-linked Deubiquitination Cell Separation After Cytokinesis
Tagcloud ?			acidic allosterically ash2l box compass composed concave erythroid forming heterodimer interface kmt2 lysine methyltransferase methyltransferases mll1 mutational rbbp5 referred ryanodine set1 spia spry stimulates switch trithorax trxg wdr5 wrad
Tagcloud (Difference) ?			acidic allosterically ash2l box compass composed concave erythroid forming heterodimer interface kmt2 lysine methyltransferase methyltransferases mll1 mutational rbbp5 referred ryanodine set1 spia spry stimulates switch trithorax trxg wdr5 wrad
Tagcloud (Intersection) ?