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ARFGEF1 and MYO9B
Number of citations of the paper that reports this interaction (PMID
15644318
)
6
Data Source:
HPRD
(in vitro, two hybrid)
ARFGEF1
MYO9B
Gene Name
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
myosin IXB
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Nucleoplasm
Nucleolus
Cytoplasm
Golgi Apparatus
Trans-Golgi Network
Cytosol
Nuclear Matrix
Small Nuclear Ribonucleoprotein Complex
Perinuclear Region Of Cytoplasm
Ruffle
Cytoplasm
Cytosol
Cell Cortex
Actin Cytoskeleton
Membrane
Myosin Complex
Lamellipodium
Filamentous Actin
Filopodium Tip
Perinuclear Region Of Cytoplasm
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
ARF Guanyl-nucleotide Exchange Factor Activity
Protein Binding
ARF GTPase Activator Activity
Myosin Binding
Protein Kinase A Regulatory Subunit Binding
Microfilament Motor Activity
Actin Binding
Rho GTPase Activator Activity
Protein Binding
Calmodulin Binding
ATP Binding
Zinc Ion Binding
ATPase Activity
Actin-dependent ATPase Activity
Protein Homodimerization Activity
ATP-dependent Protein Binding
ADP Binding
Actin Filament Binding
Biological Process
Exocytosis
Golgi Organization
Endomembrane System Organization
Protein Transport
Vesicle-mediated Transport
Negative Regulation Of Actin Filament Polymerization
Regulation Of ARF Protein Signal Transduction
Negative Regulation Of Rho GTPase Activity
Positive Regulation Of GTPase Activity
Positive Regulation Of Protein Glycosylation In Golgi
Positive Regulation Of Wound Healing
Regulation Of Establishment Of Cell Polarity
Monocyte Chemotaxis
Small GTPase Mediated Signal Transduction
Rho Protein Signal Transduction
Establishment Of Cell Polarity
Actin Filament-based Movement
ARF Protein Signal Transduction
Positive Regulation Of Rho GTPase Activity
Macrophage Chemotaxis
Regulation Of Small GTPase Mediated Signal Transduction
Lamellipodium Morphogenesis
Pathways
Rho GTPase cycle
Signaling by Rho GTPases
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Drugs
Diseases
GWAS
Height (
20881960
)
Protein-Protein Interactions
4 interactors:
ARFGEF2
DPY30
FKBP2
MYO9B
6 interactors:
ACTA1
ARFGEF1
CALM1
LRRC41
MOB4
PKN2
Entrez ID
10565
4650
HPRD ID
09163
03677
Ensembl ID
ENSG00000066777
ENSG00000099331
Uniprot IDs
Q9Y6D6
B0I1T6
Q13459
Q4LE74
Q8WVD2
PDB IDs
3LTL
Enriched GO Terms of Interacting Partners
?
Regulation Of Cytokinesis
Positive Regulation Of Protein Glycosylation In Golgi
Skeletal Muscle Fiber Adaptation
Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity
Positive Regulation Of Protein Glycosylation
Regulation Of High Voltage-gated Calcium Channel Activity
Muscle Contraction
Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Skeletal Muscle Thin Filament Assembly
Regulation Of Cell Division
Muscle System Process
Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Skeletal Myofibril Assembly
Skeletal Muscle Adaptation
Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Regulation Of Protein Glycosylation
Response To Metal Ion
Exocytosis
Detection Of Calcium Ion
Regulation Of Cell Communication By Electrical Coupling
Positive Regulation Of Phosphoprotein Phosphatase Activity
Negative Regulation Of Rho GTPase Activity
Positive Regulation Of Glycoprotein Biosynthetic Process
Positive Regulation Of Peptidyl-threonine Phosphorylation
Positive Regulation Of Glycoprotein Metabolic Process
Positive Regulation Of Protein Autophosphorylation
Positive Regulation Of Nitric-oxide Synthase Activity
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Glycogen Catabolic Process
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Negative Regulation Of Peptidyl-threonine Phosphorylation
Regulation Of Voltage-gated Calcium Channel Activity
Positive Regulation Of Protein Dephosphorylation
Negative Regulation Of Ras GTPase Activity
Negative Regulation Of Cation Channel Activity
Polysaccharide Catabolic Process
Positive Regulation Of Viral Genome Replication
Response To Inorganic Substance
Response To Steroid Hormone
Positive Regulation Of Monooxygenase Activity
Skeletal Muscle Fiber Development
Regulation Of Cell Cycle Process
Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling
Positive Regulation Of Calcium Ion Transmembrane Transporter Activity
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Secretion By Cell
Regulation Of Rhodopsin Mediated Signaling Pathway
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Activation Of Adenylate Cyclase Activity
Nitric Oxide Metabolic Process
Tagcloud
?
akap6
atf7
atxn1
bmpr2
categorize
deltan
eef1a1
grip2
gtf2f1
interactors
jbd
jbds
jnk1alpha1
jnk3
jnk3alpha1
jnks
kcne4
nnat
pias1
ptgds
ptpn2
rabgap1
rusc2
shank1
sumo1
sypl1
tkt
topbp1
znf668
Tagcloud (Difference)
?
akap6
atf7
atxn1
bmpr2
categorize
deltan
eef1a1
grip2
gtf2f1
interactors
jbd
jbds
jnk1alpha1
jnk3
jnk3alpha1
jnks
kcne4
nnat
pias1
ptgds
ptpn2
rabgap1
rusc2
shank1
sumo1
sypl1
tkt
topbp1
znf668
Tagcloud (Intersection)
?