ANP32B and CHAF1A

Number of citations of the paper that reports this interaction (PubMedID 21209461)
64

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ANP32B	CHAF1A
Description		acidic nuclear phosphoprotein 32 family member B	chromatin assembly factor 1 subunit A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Extracellular Exosome	Chromatin Nucleus Protein-containing Complex CAF-1 Complex
	Molecular Function	Protein Binding Histone Binding RNA Polymerase Binding	Chromatin Binding Protein Binding Identical Protein Binding Unfolded Protein Binding Chromo Shadow Domain Binding
	Biological Process	Vasculature Development Nucleosome Assembly Ventricular System Development Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cell Differentiation Positive Regulation Of Protein Export From Nucleus Inner Ear Development Roof Of Mouth Development	DNA Replication DNA Repair Chromatin Organization Nucleosome Assembly DNA Replication-dependent Chromatin Assembly DNA Damage Response
Pathways
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Coronary artery disease ( 29212778) Eosinophil count ( 32888494) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 27863252 32888494) Serum thyroid-stimulating hormone levels ( 25436638)	Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 27863252 28957414 32888494)
Interacting Genes		42 interacting genes: AIM2 APC APP AURKA BAX BCL10 BEND7 BUB1 CHAF1A CSNK2A1 DCC DNTTIP1 ELAVL1 ESR1 FAM217B FAM3A FBXW7 H2AC1 H2BC1 H3C1 H4C1 HNF4A KLF5 KPNA1 KPNA5 MCC MEOX2 MLH3 MYNN PMS2 POLR1A PTEN PTPN12 PTPRJ SDCBP SMAD2 SMARCD1 STK11 TLR2 UCHL5 XPO1 YAF2	47 interacting genes: ANP32A ANP32B ASF1A ASF1B BLM CBX1 CBX5 CDC7 CDK2 CHAF1B CREBBP DBF4 DDX41 H3-4 H3C6 HMGB2 LZTR1 MBD1 MEI4 MSH6 NOTO PABPC1 PAX6 PCBD2 PCNA POU6F2 RBFOX2 REL SERTAD1 SET SPOP STAT5B SUMO1 SUMO2 SUMO3 TCERG1 TCF4 TRIB3 TRIM28 XRCC5 XRCC6 YWHAB YWHAE YWHAG YWHAQ ZNF408 ZNF620
Entrez ID		10541	10036
HPRD ID		09803	03148
Ensembl ID		ENSG00000136938	ENSG00000167670
Uniprot IDs		Q92688	Q13111
PDB IDs		2ELL 2RR6 8R1J 8R1L	7Y5K 7Y5L 7Y5O 7Y5U 7Y5V 7Y60 7Y61 8IQF 8IQG 8J6S 8J6T
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Chromatin Remodeling Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Protein Heterodimerization Activity Regulation Of Macromolecule Metabolic Process Developmental Growth DNA Binding Chromatin Organization Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Multicellular Organismal Process Regulation Of Developmental Process Regulation Of Primary Metabolic Process Positive Regulation Of Catabolic Process Regulation Of Signal Transduction Programmed Cell Death Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cell Death Regulation Of Wnt Signaling Pathway Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Communication DNA Damage Response Regulation Of Signaling Microglia Development Satellite Cell Activation Involved In Skeletal Muscle Regeneration Nucleosome Organization Chromatin Binding Chromosome Organization Protein Localization To Organelle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Population Proliferation Regulation Of Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Protein Catabolic Process Regulation Of Cellular Component Organization Regulation Of Proteolysis Negative Regulation Of Metabolic Process Cytosol Apoptotic Process Regulation Of Gene Expression Kinetochore Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Population Proliferation Structural Constituent Of Chromatin Mismatch Repair Complex Positive Regulation Of RNA Metabolic Process Protein Dephosphorylation	Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Nucleoplasm Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Chromatin Organization DNA Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Remodeling Nucleic Acid Metabolic Process Nucleosome Assembly DNA Repair Regulation Of Metabolic Process Regulation Of Gene Expression DNA Damage Response Negative Regulation Of RNA Metabolic Process DNA Replication-dependent Chromatin Assembly Protein-DNA Complex Assembly Regulation Of Macromolecule Biosynthetic Process Nucleosome Organization Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin DNA Recombination Regulation Of Transcription By RNA Polymerase II Chromosome, Telomeric Region Damaged DNA Binding Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Chromatin Binding Cellular Response To Stress Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein-containing Complex Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process DNA Binding Chromosome Organization Positive Regulation Of Macromolecule Metabolic Process Macromolecule Metabolic Process Telomere Organization ATP-dependent Activity, Acting On DNA Ubiquitin Protein Ligase Binding Chromosome Positive Regulation Of Metabolic Process Recombinational Repair Double-strand Break Repair
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