ANP32B and H2AC1

Number of citations of the paper that reports this interaction (PubMedID 18039846)
53

Data Source:
BioGRID (pull down)

		ANP32B	H2AC1
Description		acidic nuclear phosphoprotein 32 family member B	H2A clustered histone 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Extracellular Exosome	Chromosome, Telomeric Region Nucleosome Female Germ Cell Nucleus Nucleus Chromosome Extracellular Exosome
	Molecular Function	Protein Binding Histone Binding RNA Polymerase Binding	DNA Binding Structural Constituent Of Chromatin Protein Heterodimerization Activity
	Biological Process	Vasculature Development Nucleosome Assembly Ventricular System Development Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cell Differentiation Positive Regulation Of Protein Export From Nucleus Inner Ear Development Roof Of Mouth Development	Chromatin Organization Heterochromatin Formation
Pathways			HDACs deacetylate histones HATs acetylate histones HATs acetylate histones RMTs methylate histone arginines UCH proteinases Ub-specific processing proteases Metalloprotease DUBs HCMV Early Events HCMV Late Events
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Coronary artery disease ( 29212778) Eosinophil count ( 32888494) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 27863252 32888494) Serum thyroid-stimulating hormone levels ( 25436638)
Interacting Genes		42 interacting genes: AIM2 APC APP AURKA BAX BCL10 BEND7 BUB1 CHAF1A CSNK2A1 DCC DNTTIP1 ELAVL1 ESR1 FAM217B FAM3A FBXW7 H2AC1 H2BC1 H3C1 H4C1 HNF4A KLF5 KPNA1 KPNA5 MCC MEOX2 MLH3 MYNN PMS2 POLR1A PTEN PTPN12 PTPRJ SDCBP SMAD2 SMARCD1 STK11 TLR2 UCHL5 XPO1 YAF2	5 interacting genes: ANP32B HDAC1 HDAC2 HDAC3 TLE3
Entrez ID		10541	221613
HPRD ID		09803	13653
Ensembl ID		ENSG00000136938	ENSG00000164508
Uniprot IDs		Q92688	Q96QV6
PDB IDs		2ELL 2RR6 8R1J 8R1L	5GSU 5GT0
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Chromatin Remodeling Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Protein Heterodimerization Activity Regulation Of Macromolecule Metabolic Process Developmental Growth DNA Binding Chromatin Organization Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Multicellular Organismal Process Regulation Of Developmental Process Regulation Of Primary Metabolic Process Positive Regulation Of Catabolic Process Regulation Of Signal Transduction Programmed Cell Death Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cell Death Regulation Of Wnt Signaling Pathway Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Communication DNA Damage Response Regulation Of Signaling Microglia Development Satellite Cell Activation Involved In Skeletal Muscle Regeneration Nucleosome Organization Chromatin Binding Chromosome Organization Protein Localization To Organelle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Population Proliferation Regulation Of Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Protein Catabolic Process Regulation Of Cellular Component Organization Regulation Of Proteolysis Negative Regulation Of Metabolic Process Cytosol Apoptotic Process Regulation Of Gene Expression Kinetochore Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Population Proliferation Structural Constituent Of Chromatin Mismatch Repair Complex Positive Regulation Of RNA Metabolic Process Protein Dephosphorylation	Protein Lysine Delactylase Activity Protein Decrotonylase Activity Histone Decrotonylase Activity Histone Deacetylase Activity, Hydrolytic Mechanism Protein Lysine Deacetylase Activity Histone Deacetylase Activity NF-kappaB Binding Protein De-2-hydroxyisobutyrylase Activity Histone Deacetylase Complex Fungiform Papilla Formation Circadian Regulation Of Gene Expression Hair Follicle Placode Formation Deacetylase Activity Histone Deacetylase Binding Circadian Rhythm Eyelid Development In Camera-type Eye Heterochromatin Formation Protein Deacetylation Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides NuRD Complex Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Myotube Differentiation Chromatin Remodeling DNA-binding Transcription Factor Binding Positive Regulation Of Oligodendrocyte Differentiation Sin3-type Complex Transcription Corepressor Activity Regulation Of Cell Fate Specification Negative Regulation Of Stem Cell Population Maintenance Macromolecule Deacylation Chromatin Organization Negative Regulation Of Apoptotic Process Rhythmic Process Negative Regulation Of Programmed Cell Death Epigenetic Regulation Of Gene Expression Negative Regulation Of Developmental Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Protein Export From Nucleus Positive Regulation Of Glial Cell Differentiation Nucleosomal DNA Binding Regulation Of Oligodendrocyte Differentiation Negative Regulation Of Striated Muscle Cell Differentiation Regulation Of Myotube Differentiation Regulation Of Cell Fate Commitment Positive Regulation Of Stem Cell Population Maintenance Transcription Corepressor Binding Embryonic Digit Morphogenesis Negative Regulation Of Multicellular Organismal Process Enzyme Binding
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