CHAF1A and ANP32B

Number of citations of the paper that reports this interaction (PMID 21209461)
3

Data Source:
BioGRID (affinity chromatography technology, pull down)

		CHAF1A	ANP32B
Gene Name		chromatin assembly factor 1, subunit A (p150)	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin CAF-1 Complex Protein Complex	Nucleus Nucleolus Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Chromatin Binding Protein Binding Identical Protein Binding Unfolded Protein Binding Chromo Shadow Domain Binding	Histone Binding RNA Polymerase Binding
	Biological Process	DNA Replication DNA Repair DNA Replication-dependent Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Complex Assembly Cell Cycle Chromatin Assembly	Vasculature Development Nucleosome Assembly Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Ventricular System Development Negative Regulation Of Cell Differentiation Positive Regulation Of Protein Export From Nucleus Inner Ear Development Palate Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		37 interactors: ANP32A ANP32B ASF1A ASF1B BLM CBX1 CBX5 CDC7 CDK2 CHAF1B DBF4 DDX41 HIST1H3E HIST3H3 HMGB2 LZTR1 MBD1 MSH6 PABPC1 PCBD2 PCNA RBFOX2 REL SET SUMO1 SUMO2 SUMO3 TCERG1 TCF4 TRIM28 XRCC5 XRCC6 YWHAB YWHAE YWHAG YWHAQ ZNF408	14 interactors: APP CHAF1A CSNK2A1 ELAVL1 HNF4A KPNA1 KPNA5 MEOX2 POLR1A SDCBP SMAD2 SMARCD1 UCHL5 XPO1
Entrez ID		10036	10541
HPRD ID		03148	09803
Ensembl ID		ENSG00000167670	ENSG00000136938
Uniprot IDs		Q13111	Q92688
PDB IDs			2ELL 2RR6
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process DNA Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Conformation Change Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process DNA Repair Protein-DNA Complex Assembly Chromosome Organization Nitrogen Compound Metabolic Process Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Chromatin Assembly Nucleosome Organization Cellular Response To DNA Damage Stimulus Chromatin Assembly Or Disassembly Regulation Of Cellular Process Positive Regulation Of Cellular Metabolic Process DNA Packaging Positive Regulation Of Metabolic Process Cellular Response To Stress Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Protein Sumoylation DNA Recombination Positive Regulation Of Intracellular Transport Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Response To Stress Telomere Maintenance Organelle Organization DNA Replication Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cellular Macromolecule Biosynthetic Process Protein Complex Assembly Macromolecule Biosynthetic Process Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Cellular Metabolic Process	Gene Expression Regulation Of Metabolic Process Regulation Of Gene Expression Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Nitrogen Compound Metabolic Process NLS-bearing Protein Import Into Nucleus Transforming Growth Factor Beta Receptor Signaling Pathway Protein Localization To Nucleus Enzyme Linked Receptor Protein Signaling Pathway Intracellular Transport Of Virus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Transcription, DNA-templated RNA Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Signal Transduction Involved In Regulation Of Gene Expression Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Transcription, DNA-templated Response To Transforming Growth Factor Beta Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression, Epigenetic Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Organic Substance Nucleocytoplasmic Transport Nuclear Transport Negative Regulation Of Endopeptidase Activity SMAD Protein Signal Transduction Regulation Of Signal Transduction Negative Regulation Of Peptidase Activity Establishment Of Localization In Cell Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Neuron Death Signal Transduction
Tagcloud ?		3a aggressive cohorts concept driven gsea intact malignancies malignancy mcm3 mcm6 mdm2 multifactorial networks neuroblastoma nutlin oncogene opposing overcome p53 potently reciprocally repressed repression rrm2 signature signatures subset worst	acidic anionic belongs chaperone chaperones compose concave convex curved elusive eviction framework helical hydrophobic leucine lrr lrrs modulating nucleosome nucleosomes onto phosphoprotein possesses repeats shares sheet side
Tagcloud (Difference) ?		3a aggressive cohorts concept driven gsea intact malignancies malignancy mcm3 mcm6 mdm2 multifactorial networks neuroblastoma nutlin oncogene opposing overcome p53 potently reciprocally repressed repression rrm2 signature signatures subset worst	acidic anionic belongs chaperone chaperones compose concave convex curved elusive eviction framework helical hydrophobic leucine lrr lrrs modulating nucleosome nucleosomes onto phosphoprotein possesses repeats shares sheet side
Tagcloud (Intersection) ?