CHAF1A and ANP32A

Number of citations of the paper that reports this interaction (PubMedID 21209461)
64

Data Source:
BioGRID (pull down)

		CHAF1A	ANP32A
Description		chromatin assembly factor 1 subunit A	acidic nuclear phosphoprotein 32 family member A
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GO Annotations	Cellular Component	Chromatin Nucleus Protein-containing Complex CAF-1 Complex	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Chromatin Binding Protein Binding Identical Protein Binding Unfolded Protein Binding Chromo Shadow Domain Binding	RNA Binding Protein Binding Histone Binding
	Biological Process	DNA Replication DNA Repair Chromatin Organization Nucleosome Assembly DNA Replication-dependent Chromatin Assembly DNA Damage Response	Nucleocytoplasmic Transport Intracellular Signal Transduction Regulation Of Apoptotic Process
Pathways			HuR (ELAVL1) binds and stabilizes mRNA
Drugs
Diseases
GWAS		Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 27863252 28957414 32888494)	Esophageal cancer ( 21642993)
Interacting Genes		47 interacting genes: ANP32A ANP32B ASF1A ASF1B BLM CBX1 CBX5 CDC7 CDK2 CHAF1B CREBBP DBF4 DDX41 H3-4 H3C6 HMGB2 LZTR1 MBD1 MEI4 MSH6 NOTO PABPC1 PAX6 PCBD2 PCNA POU6F2 RBFOX2 REL SERTAD1 SET SPOP STAT5B SUMO1 SUMO2 SUMO3 TCERG1 TCF4 TRIB3 TRIM28 XRCC5 XRCC6 YWHAB YWHAE YWHAG YWHAQ ZNF408 ZNF620	30 interacting genes: ADAP1 APEX1 ATXN1 AXIN1 CHAF1A E4F1 ELAVL1 H2AC20 H2BC21 H3-4 H3C1 H3C15 H4C1 H4C16 HSPB3 KPNA1 KPNA5 KPNA6 LHX3 LINC00632 MAP1B NSFL1C PCBP1 PGR PPARG PTPRC SET TAF1A THRB XPO1
Entrez ID		10036	8125
HPRD ID		03148	09014
Ensembl ID		ENSG00000167670	ENSG00000140350
Uniprot IDs		Q13111	A0A384P5U2 P39687
PDB IDs		7Y5K 7Y5L 7Y5O 7Y5U 7Y5V 7Y60 7Y61 8IQF 8IQG 8J6S 8J6T	2JE0 2JE1 4XOS 6XZQ 8RMR 8RN0 8RNA 8RNB 8RNC
Enriched GO Terms of Interacting Partners?		Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Nucleoplasm Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Chromatin Organization DNA Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Remodeling Nucleic Acid Metabolic Process Nucleosome Assembly DNA Repair Regulation Of Metabolic Process Regulation Of Gene Expression DNA Damage Response Negative Regulation Of RNA Metabolic Process DNA Replication-dependent Chromatin Assembly Protein-DNA Complex Assembly Regulation Of Macromolecule Biosynthetic Process Nucleosome Organization Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin DNA Recombination Regulation Of Transcription By RNA Polymerase II Chromosome, Telomeric Region Damaged DNA Binding Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Chromatin Binding Cellular Response To Stress Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein-containing Complex Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process DNA Binding Chromosome Organization Positive Regulation Of Macromolecule Metabolic Process Macromolecule Metabolic Process Telomere Organization ATP-dependent Activity, Acting On DNA Ubiquitin Protein Ligase Binding Chromosome Positive Regulation Of Metabolic Process Recombinational Repair Double-strand Break Repair	Nucleosome Assembly Nucleosome Organization Structural Constituent Of Chromatin Nucleus Protein-DNA Complex Assembly Nucleosome Chromatin Remodeling DNA Binding Chromatin Organization Nuclear Transport Nucleocytoplasmic Transport NLS-dependent Protein Nuclear Import Complex Nucleoplasm Protein Heterodimerization Activity Nuclear Import Signal Receptor Activity Nuclear Localization Sequence Binding Negative Regulation Of Macromolecule Biosynthetic Process NLS-bearing Protein Import Into Nucleus Protein Localization To Organelle Negative Regulation Of Biosynthetic Process Protein Localization To Nucleus Negative Regulation Of RNA Metabolic Process Chromosome Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein-containing Complex Assembly Protein-containing Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Biosynthetic Process Protein Import Into Nucleus DNA Replication-dependent Chromatin Assembly Import Into Nucleus Telomere Organization Transcription Coactivator Binding Nuclear Receptor Activity Protein-containing Complex Organization Cellular Component Assembly Negative Regulation Of Metabolic Process Transcription By RNA Polymerase II Chromatin Binding Regulation Of Nucleobase-containing Compound Metabolic Process Establishment Of Localization In Cell Positive Regulation Of Transcription By RNA Polymerase II Chromosome, Telomeric Region Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin
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