ANP32B and KPNA5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ANP32B	KPNA5
Gene Name		acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	karyopherin alpha 5 (importin alpha 6)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Histone Binding RNA Polymerase Binding	Protein Binding Protein Transporter Activity
	Biological Process	Vasculature Development Nucleosome Assembly Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Ventricular System Development Negative Regulation Of Cell Differentiation Positive Regulation Of Protein Export From Nucleus Inner Ear Development Palate Development	NLS-bearing Protein Import Into Nucleus Cytokine-mediated Signaling Pathway
Pathways			ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS			Telomere length ( 21460395)
Protein-Protein Interactions		14 interactors: APP CHAF1A CSNK2A1 ELAVL1 HNF4A KPNA1 KPNA5 MEOX2 POLR1A SDCBP SMAD2 SMARCD1 UCHL5 XPO1	7 interactors: ANP32A ANP32B BRMS1 CDKN1B IL32 NUP50 SPOPL
Entrez ID		10541	3841
HPRD ID		09803	05179
Ensembl ID		ENSG00000136938	ENSG00000196911
Uniprot IDs		Q92688	O15131
PDB IDs		2ELL 2RR6
Enriched GO Terms of Interacting Partners?		Gene Expression Regulation Of Metabolic Process Regulation Of Gene Expression Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Nitrogen Compound Metabolic Process NLS-bearing Protein Import Into Nucleus Transforming Growth Factor Beta Receptor Signaling Pathway Protein Localization To Nucleus Enzyme Linked Receptor Protein Signaling Pathway Intracellular Transport Of Virus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Transcription, DNA-templated RNA Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Signal Transduction Involved In Regulation Of Gene Expression Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Transcription, DNA-templated Response To Transforming Growth Factor Beta Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression, Epigenetic Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Organic Substance Nucleocytoplasmic Transport Nuclear Transport Negative Regulation Of Endopeptidase Activity SMAD Protein Signal Transduction Regulation Of Signal Transduction Negative Regulation Of Peptidase Activity Establishment Of Localization In Cell Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Neuron Death Signal Transduction	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Positive Regulation Of Peptidase Activity Positive Regulation Of Anoikis Inner Ear Development Regulation Of Cellular Protein Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Autophagic Cell Death Ear Development Regulation Of Protein Metabolic Process Protein Processing Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Export From Nucleus
Tagcloud ?		acidic anionic belongs chaperone chaperones compose concave convex curved elusive eviction framework helical hydrophobic leucine lrr lrrs modulating nucleosome nucleosomes onto phosphoprotein possesses repeats shares sheet side	accurately adam12 cancers candidate centb1 centg1 dip2c exome gli1 grin2d hdlbp hedgehog ikbkb infrequent involvement kb mutation nfkb1 notch notch1 otof pik3ca point prevalence recurring sequencing somatic strengthen substantial
Tagcloud (Difference) ?		acidic anionic belongs chaperone chaperones compose concave convex curved elusive eviction framework helical hydrophobic leucine lrr lrrs modulating nucleosome nucleosomes onto phosphoprotein possesses repeats shares sheet side	accurately adam12 cancers candidate centb1 centg1 dip2c exome gli1 grin2d hdlbp hedgehog ikbkb infrequent involvement kb mutation nfkb1 notch notch1 otof pik3ca point prevalence recurring sequencing somatic strengthen substantial
Tagcloud (Intersection) ?