RAD23B and PAQR3

Number of citations of the paper that reports this interaction (PubMedID 28473198)
0

Data Source:
BioGRID (pull down)

		RAD23B	PAQR3
Description		RAD23 nucleotide excision repair protein B	progestin and adipoQ receptor family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Cytosol XPC Complex	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Proteasome Binding DNA Damage Sensor Activity	Protein Binding Protein-membrane Adaptor Activity Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	DNA Repair Nucleotide-excision Repair DNA Damage Response Spermatogenesis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Embryonic Organ Development Cellular Response To Interleukin-7	Negative Regulation Of Protein Phosphorylation NLS-bearing Protein Import Into Nucleus Negative Regulation Of Neuron Projection Development Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Peptidyl-serine Phosphorylation Protein Localization To Golgi Apparatus Peroxisome Proliferator Activated Receptor Signaling Pathway Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of MAP Kinase Activity Positive Regulation Of Cholesterol Biosynthetic Process Protein Maturation Positive Regulation Of SREBP Signaling Pathway
Pathways		N-glycan trimming in the ER and Calnexin/Calreticulin cycle Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER	Negative regulation of MAPK pathway
Drugs
Diseases
GWAS		Body mass index ( 20966902) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 21263130) Chronotype ( 30696823) Cutaneous malignant melanoma ( 26237428) Melanoma ( 28212542) Prostate cancer ( 23023329)	Chronotype ( 30696823) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Parkinson's disease ( 26227905)
Interacting Genes		31 interacting genes: ADRM1 ATXN3 CALM1 CEBPA DBI DEAF1 HIP1 HMGB1 MKRN1 MLH1 MPG NGLY1 OGT PAQR3 PAX3 PNMA5 POU6F2 PSMD4 PUF60 RPA1 RSC1A1 TAX1BP1 TDG UBA2 UBB UBC UBE3A USP25 WWP2 XPC ZFAND5	3 interacting genes: BTRC PPARA RAD23B
Entrez ID		5887	152559
HPRD ID		06772	17819
Ensembl ID		ENSG00000119318	ENSG00000163291
Uniprot IDs		B7Z4W4 P54727	Q6TCH7
PDB IDs		1P1A 1PVE 1UEL 8EBS 8EBV 8EBW
Enriched GO Terms of Interacting Partners?		Nucleus Macromolecule Metabolic Process Damaged DNA Binding Base-excision Repair SUMO Binding Macromolecule Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Catabolic Process Regulation Of Proteolysis Nucleoplasm Modification-dependent Protein Catabolic Process Post-translational Protein Modification Regulation Of Ubiquitin-dependent Protein Catabolic Process Mismatch Repair Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Proteolysis DNA Repair Condensed Chromosome Single-stranded DNA Binding Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Bubble DNA Binding Protein Ubiquitination Protein Catabolic Process Nucleic Acid Metabolic Process Nucleotide-excision Repair DNA N-glycosylase Activity Protein Polyubiquitination Mismatched DNA Binding Proteasomal Protein Catabolic Process Proteasome Complex Positive Regulation Of TORC1 Signaling Protein Metabolic Process DNA Metabolic Process Protein Tag Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Base-excision Repair, AP Site Formation Protein Modification Process DNA Damage Response Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of TOR Signaling Protein Binding Regulation Of Primary Metabolic Process DNA Binding Regulation Of TORC1 Signaling Cell Development	Negative Regulation Of Appetite Response To Nutrient Levels Negative Regulation Of Glycolytic Process Regulation Of Circadian Rhythm Cellular Response To Fructose Stimulus Animal Organ Development Negative Regulation Of Cholesterol Storage Regulation Of Response To Food MDM2/MDM4 Family Protein Binding Enamel Mineralization Response To Fructose Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Hepatocyte Apoptotic Process Peroxisome Proliferator Activated Receptor Signaling Pathway Negative Regulation Of Catabolic Process Regulation Of Transformation Of Host Cell By Virus Cellular Response To Nutrient Levels Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of ATP Biosynthetic Process Tooth Mineralization Rhythmic Process NFAT Protein Binding Positive Regulation Of Transformation Of Host Cell By Virus Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of ATP Biosynthetic Process Behavioral Response To Nicotine Positive Regulation Of Fatty Acid Beta-oxidation Mitogen-activated Protein Kinase Kinase Kinase Binding Positive Regulation Of Fatty Acid Oxidation Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process DNA Damage Sensor Activity Cellular Response To Interleukin-7 Proteasomal Protein Catabolic Process Proteasome Binding XPC Complex Regulation Of Protein Catabolic Process Response To Interleukin-7 Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Circadian Rhythm Ubiquitin Ligase Activator Activity Mammary Gland Epithelial Cell Proliferation Morphogenesis Of An Epithelium Protein Phosphorylated Amino Acid Binding Tissue Morphogenesis Positive Regulation Of T Cell Receptor Signaling Pathway
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