RAD23B and RSC1A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RAD23B	RSC1A1
Description		RAD23 nucleotide excision repair protein B	regulator of solute carriers 1
Image			No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Cytosol XPC Complex	Nucleus Nucleoplasm Golgi Apparatus Plasma Membrane Membrane Cell Junction
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Proteasome Binding DNA Damage Sensor Activity	Protein Binding Sodium Channel Inhibitor Activity
	Biological Process	DNA Repair Nucleotide-excision Repair DNA Damage Response Spermatogenesis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Embryonic Organ Development Cellular Response To Interleukin-7	Negative Regulation Of D-glucose Transmembrane Transport Negative Regulation Of Nucleoside Transport Negative Regulation Of Golgi To Plasma Membrane Protein Transport Negative Regulation Of Transport Negative Regulation Of Protein Localization To Plasma Membrane
Pathways		N-glycan trimming in the ER and Calnexin/Calreticulin cycle Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER	SLC-mediated transport of organic cations Intestinal hexose absorption
Drugs
Diseases
GWAS		Body mass index ( 20966902) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 21263130) Chronotype ( 30696823) Cutaneous malignant melanoma ( 26237428) Melanoma ( 28212542) Prostate cancer ( 23023329)	Alcoholic chronic pancreatitis ( 28754779)
Interacting Genes		31 interacting genes: ADRM1 ATXN3 CALM1 CEBPA DBI DEAF1 HIP1 HMGB1 MKRN1 MLH1 MPG NGLY1 OGT PAQR3 PAX3 PNMA5 POU6F2 PSMD4 PUF60 RPA1 RSC1A1 TAX1BP1 TDG UBA2 UBB UBC UBE3A USP25 WWP2 XPC ZFAND5	3 interacting genes: LSM8 ODC1 RAD23B
Entrez ID		5887	6248
HPRD ID		06772	15994
Ensembl ID		ENSG00000119318	ENSG00000215695
Uniprot IDs		B7Z4W4 P54727	Q92681
PDB IDs		1P1A 1PVE 1UEL 8EBS 8EBV 8EBW
Enriched GO Terms of Interacting Partners?		Nucleus Macromolecule Metabolic Process Damaged DNA Binding Base-excision Repair SUMO Binding Macromolecule Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Catabolic Process Regulation Of Proteolysis Nucleoplasm Modification-dependent Protein Catabolic Process Post-translational Protein Modification Regulation Of Ubiquitin-dependent Protein Catabolic Process Mismatch Repair Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Proteolysis DNA Repair Condensed Chromosome Single-stranded DNA Binding Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Bubble DNA Binding Protein Ubiquitination Protein Catabolic Process Nucleic Acid Metabolic Process Nucleotide-excision Repair DNA N-glycosylase Activity Protein Polyubiquitination Mismatched DNA Binding Proteasomal Protein Catabolic Process Proteasome Complex Positive Regulation Of TORC1 Signaling Protein Metabolic Process DNA Metabolic Process Protein Tag Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Base-excision Repair, AP Site Formation Protein Modification Process DNA Damage Response Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of TOR Signaling Protein Binding Regulation Of Primary Metabolic Process DNA Binding Regulation Of TORC1 Signaling Cell Development	MAML1-RBP-Jkappa- ICN1 Complex Positive Regulation Of Ephrin Receptor Signaling Pathway Club Cell Differentiation Epidermal Cell Fate Specification Endocardium Morphogenesis RNA Polymerase II-specific DNA-binding Transcription Factor Binding Embryonic Organ Development Pulmonary Valve Development Blood Vessel Endothelial Cell Fate Specification Blood Vessel Lumenization Arterial Endothelial Cell Fate Commitment Endothelial Cell Fate Specification Auditory Receptor Cell Fate Commitment Regulation Of Cell Adhesion Involved In Heart Morphogenesis Ornithine Decarboxylase Activity Putrescine Biosynthetic Process From Arginine, Via Ornithine DNA Damage Sensor Activity XPC Complex Endocardium Development Putrescine Biosynthetic Process Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Aortic Valve Development Hair Follicle Maturation Semi-lunar Valve Development Positive Regulation Of Transcription Of Notch Receptor Target Lsm2-8 Complex Sebaceous Gland Development Dorsal Aorta Morphogenesis Putrescine Metabolic Process Animal Organ Development U6 SnRNP Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Ventricular Trabecula Myocardium Morphogenesis Regulation Of Timing Of Cell Differentiation Regulation Of Development, Heterochronic Cardiac Muscle Cell Myoblast Differentiation Endothelial Tube Morphogenesis Heart Field Specification Atrioventricular Canal Development Epithelial Cell Fate Commitment Secondary Heart Field Specification Cardioblast Differentiation Cardiac Left Ventricle Morphogenesis Polyamine Biosynthetic Process Regulation Of Protein Catabolic Process Cellular Response To Interleukin-7 U6 SnRNA Binding Response To Interleukin-7 Specification Of Animal Organ Identity Regulation Of Cell Proliferation Involved In Heart Morphogenesis
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