RAD23B and ZFAND5

Number of citations of the paper that reports this interaction (PubMedID 16424905)
60

Data Source:
HPRD (in vitro, two hybrid)

		RAD23B	ZFAND5
Description		RAD23 nucleotide excision repair protein B	zinc finger AN1-type containing 5
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GO Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Cytosol XPC Complex	Cytoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Proteasome Binding DNA Damage Sensor Activity	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	DNA Repair Nucleotide-excision Repair DNA Damage Response Spermatogenesis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Embryonic Organ Development Cellular Response To Interleukin-7	In Utero Embryonic Development Vasculature Development Respiratory System Process Fibroblast Migration Platelet-derived Growth Factor Receptor Signaling Pathway Skeletal System Morphogenesis Smooth Muscle Tissue Development Face Development
Pathways		N-glycan trimming in the ER and Calnexin/Calreticulin cycle Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS		Body mass index ( 20966902) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 21263130) Chronotype ( 30696823) Cutaneous malignant melanoma ( 26237428) Melanoma ( 28212542) Prostate cancer ( 23023329)	Sensorimotor dexterity ( 31596458)
Interacting Genes		31 interacting genes: ADRM1 ATXN3 CALM1 CEBPA DBI DEAF1 HIP1 HMGB1 MKRN1 MLH1 MPG NGLY1 OGT PAQR3 PAX3 PNMA5 POU6F2 PSMD4 PUF60 RPA1 RSC1A1 TAX1BP1 TDG UBA2 UBB UBC UBE3A USP25 WWP2 XPC ZFAND5	14 interacting genes: APP CCNB1 IKBKG LRRK2 MAP3K1 MFHAS1 PSMD6 PTTG1 RAD23B RIPK1 SMURF1 TNFAIP3 TRAF6 UBC
Entrez ID		5887	7763
HPRD ID		06772	05302
Ensembl ID		ENSG00000119318	ENSG00000107372
Uniprot IDs		B7Z4W4 P54727	O76080
PDB IDs		1P1A 1PVE 1UEL 8EBS 8EBV 8EBW	7QXW
Enriched GO Terms of Interacting Partners?		Nucleus Macromolecule Metabolic Process Damaged DNA Binding Base-excision Repair SUMO Binding Macromolecule Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Catabolic Process Regulation Of Proteolysis Nucleoplasm Modification-dependent Protein Catabolic Process Post-translational Protein Modification Regulation Of Ubiquitin-dependent Protein Catabolic Process Mismatch Repair Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Proteolysis DNA Repair Condensed Chromosome Single-stranded DNA Binding Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Bubble DNA Binding Protein Ubiquitination Protein Catabolic Process Nucleic Acid Metabolic Process Nucleotide-excision Repair DNA N-glycosylase Activity Protein Polyubiquitination Mismatched DNA Binding Proteasomal Protein Catabolic Process Proteasome Complex Positive Regulation Of TORC1 Signaling Protein Metabolic Process DNA Metabolic Process Protein Tag Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Base-excision Repair, AP Site Formation Protein Modification Process DNA Damage Response Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of TOR Signaling Protein Binding Regulation Of Primary Metabolic Process DNA Binding Regulation Of TORC1 Signaling Cell Development	Positive Regulation Of Protein Metabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Defense Response Negative Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Signal Transduction Cytosol Positive Regulation Of Immune System Process Regulation Of JNK Cascade Negative Regulation Of Signaling Negative Regulation Of Cell Communication Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Immune System Process Protein Metabolic Process Regulation Of Tumor Necrosis Factor Production Regulation Of Proteolysis Regulation Of Apoptotic Signaling Pathway Cellular Response To Stress Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Inflammatory Response Canonical NF-kappaB Signal Transduction Positive Regulation Of Proteolysis Positive Regulation Of MAPK Cascade Response To Stress Cellular Response To Manganese Ion JUN Kinase Kinase Kinase Activity Intracellular Signal Transduction Regulation Of Defense Response Intracellular Signaling Cassette Negative Regulation Of Apoptotic Signaling Pathway Signaling Adaptor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Cellular Response To Oxygen-containing Compound Positive Regulation Of Catabolic Process Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Intracellular Signal Transduction Response To Manganese Ion Regulation Of Immune Response Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Golgi-associated Vesicle Cytoplasm Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Ubiquitin Protein Ligase Binding Positive Regulation Of Tumor Necrosis Factor Production Cellular Response To Reactive Oxygen Species Cellular Response To Catecholamine Stimulus Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Canonical NF-kappaB Signal Transduction
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