RAD23B and PUF60

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RAD23B	PUF60
Gene Name		RAD23 homolog B (S. cerevisiae)	poly-U binding splicing factor 60KDa
Image
Gene Ontology Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Cytoplasm XPC Complex	Nucleoplasm Mitochondrion Golgi Apparatus Cyclin-dependent Protein Kinase Activating Kinase Holoenzyme Complex Ribonucleoprotein Complex
	Molecular Function	Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Binding	Nucleotide Binding DNA Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Damage Removal DNA Repair Nucleotide-excision Repair Spermatogenesis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing Apoptotic Process RNA Splicing
Pathways		Nucleotide Excision Repair Global Genomic NER (GG-NER) Formation of incision complex in GG-NER DNA Damage Recognition in GG-NER Dual incision reaction in GG-NER
Drugs
Diseases
GWAS		Body mass index ( 20966902) Breast cancer ( 21263130) Prostate cancer ( 23023329)
Protein-Protein Interactions		20 interactors: ADRM1 ATXN3 CALM1 DBI DEAF1 HMGB1 MLH1 MPG NGLY1 PAX3 PNMA5 PSMD4 PUF60 RPA1 TDG UBA2 UBB UBE3A XPC ZFAND5	30 interactors: ARL8A CACNA1A CCNC CD101 CHD3 ERG FHL2 FUBP1 HIST1H1C ID3 KIAA0907 KIAA1683 LOH12CR1 MED28 PCBP1 PPP1R16A PTBP2 QRICH1 RAD23B SAP30BP SDCBP SIAH1 SNRPF SRSF11 U2AF2 UBE2I UPF2 VIM YWHAG ZG16
Entrez ID		5887	22827
HPRD ID		06772	18051
Ensembl ID		ENSG00000119318	ENSG00000179950
Uniprot IDs		B7Z4W4 P54727	Q9UHX1
PDB IDs		1P1A 1PVE 1UEL	2DNY 2KXF 2KXH 2QFJ 3DXB 3UE2 3US5 3UWT
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Catabolic Process Catabolic Process Cellular Response To DNA Damage Stimulus DNA Repair DNA Catabolic Process Base-excision Repair DNA Metabolic Process Nitrogen Compound Metabolic Process Aromatic Compound Catabolic Process Cellular Response To Stress Response To Stress Cellular Nitrogen Compound Metabolic Process Protein Catabolic Process Mismatch Repair Cellular Metabolic Process Base-excision Repair, AP Site Formation Modification-dependent Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Nucleotide-excision Repair Mitotic DNA Damage Checkpoint Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Mitotic DNA Integrity Checkpoint Multicellular Organismal Development Positive Regulation Of Proteolysis Heterocycle Metabolic Process Deoxyribose Phosphate Catabolic Process Cellular Aromatic Compound Metabolic Process Apoptotic Process Nucleotide-excision Repair, DNA Damage Removal Anatomical Structure Development Programmed Cell Death System Development Cell Death Death Negative Regulation Of Cellular Metabolic Process Regulation Of Proteolysis Response To Abiotic Stimulus Deoxyribonucleotide Catabolic Process DNA Damage Checkpoint Nervous System Development G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Checkpoint Protein Polyubiquitination Developmental Process Behavioral Fear Response Fear Response Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Process	RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Termination Of RNA Polymerase II Transcription Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process MRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA Processing MRNA 3'-end Processing RNA 3'-end Processing Negative Regulation Of RNA Splicing Transcription From RNA Polymerase II Promoter Nuclear Export MRNA Transport RNA Processing Regulation Of Metabolic Process RNA Transport RNA Localization Regulation Of Gene Expression Membrane Depolarization During Action Potential Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Cell Death Negative Regulation Of Muscle Cell Differentiation Cerebellar Molecular Layer Development Negative Regulation Of Potassium Ion Export Positive Regulation Of SUMO Transferase Activity Vestibular Nucleus Development Nucleotide-excision Repair, DNA Damage Recognition Regulation Of Heart Rate By Hormone Negative Regulation Of Gene Expression Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Proteasomal Protein Catabolic Process Nucleocytoplasmic Transport Nuclear Transport Cerebellum Maturation Atrial Cardiac Muscle Cell Development Musculoskeletal Movement, Spinal Reflex Action Regulation Of Apoptotic Process
Tagcloud ?		a3 adoptive bioinformatic blunting dige diploid disulfide excision galactosidase hnrnpa3 hnrnpq imr90 isomerase lesser mir mirrored pdia3 permanent perturbation proteome ribonucleoprotein senescence senescent slowed synaptotagmin syncrip untranslated utrs	cadherin coding computational consisting decay downregulates enhancer fxr1 fxr2 hnrnp indicates lncrna lncrnas metastasis paired ranging remodelling ribonucleoprotein rnas rnp sf3b3 splicing stimulates suppressing translation translational trerna upregulated utr
Tagcloud (Difference) ?		a3 adoptive bioinformatic blunting dige diploid disulfide excision galactosidase hnrnpa3 hnrnpq imr90 isomerase lesser mir mirrored pdia3 permanent perturbation proteome senescence senescent slowed synaptotagmin syncrip untranslated utrs	cadherin coding computational consisting decay downregulates enhancer fxr1 fxr2 hnrnp indicates lncrna lncrnas metastasis paired ranging remodelling rnas rnp sf3b3 splicing stimulates suppressing translation translational trerna upregulated utr
Tagcloud (Intersection) ?		ribonucleoprotein