SYT7 and STX3

Number of citations: 0 (PubMedID 7791877)
Data Source: HPRD (in vitro)

		SYT7	STX3
Name		synaptotagmin 7	syntaxin 3
Structure			No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Peroxisome Peroxisomal Membrane Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Membrane Axon Transport Vesicle Membrane Phagocytic Vesicle Membrane Synaptic Vesicle Membrane Dense Core Granule Cytoplasmic Vesicle Early Phagosome Presynaptic Membrane Cell Projection Synapse Extracellular Exosome Hippocampal Mossy Fiber To CA3 Synapse Secretory Vesicle	Photoreceptor Outer Segment Photoreceptor Inner Segment Nucleus Cytoplasm Vacuole Plasma Membrane Cell-cell Junction Endomembrane System Membrane Apical Plasma Membrane Lamellipodium Secretory Granule Dendrite Growth Cone SNARE Complex Melanosome Specific Granule Azurophil Granule Zymogen Granule Membrane Neuron Projection Extracellular Exosome Schaffer Collateral - CA1 Synapse Presynapse Postsynapse Glutamatergic Synapse Plasma Membrane Bounded Cell Projection
	Molecular Function	SNARE Binding Calcium Ion Binding Protein Binding Calmodulin Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Syntaxin Binding Clathrin Binding Metal Ion Binding Calcium Ion Sensor Activity	SNARE Binding SNAP Receptor Activity Protein Binding Arachidonate Binding
	Biological Process	Plasma Membrane Repair Exocytosis Vesicle Fusion Phagocytosis Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Endocytosis Synaptic Vesicle Recycling Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Bone Remodeling Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Phagocytosis Regulation Of Insulin Secretion Positive Regulation Of Transport Regulation Of Glucagon Secretion Vesicle-mediated Cholesterol Transport Phagosome-lysosome Fusion Calcium-dependent Activation Of Synaptic Vesicle Fusion Regulation Of Synaptic Vesicle Endocytosis Short-term Synaptic Potentiation Calcium Ion Regulated Lysosome Exocytosis	Neurotransmitter Transport Intracellular Protein Transport Exocytosis Vesicle Fusion Positive Regulation Of Cell Population Proliferation Regulation Of Gene Expression Vesicle-mediated Transport Neuron Projection Development Positive Regulation Of Cell Adhesion Vesicle Docking Modulation Of Chemical Synaptic Transmission Positive Regulation Of Chemotaxis Long-term Synaptic Potentiation Membrane Fusion Organelle Membrane Fusion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface
Pathways		Neurexins and neuroligins	Other interleukin signaling
GWAS		Intelligence (MTAG) ( 29326435 ) Mean arterial pressure ( 26390057 ) Metabolite levels ( 23823483 ) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311 ) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311 )	High chromosomal aberration frequency (chromosome type) ( 31586183 )
Novel Interactors		1 novel interactors: FADS2	None recorded
Interacting Genes		8 interacting genes: AP2A1 NRXN1 SIAH1 STX1A STX2 STX3 STX4 SYNCRIP	54 interacting genes: AQP6 CD79A COQ9 CPLX2 CPLX4 CREB3L1 CYB561 DNAJC5 EBAG9 ELOVL4 ERGIC3 EVI5 FAM209A FXYD3 GPR152 GPX8 JAGN1 LMNA MANBAL MGST3 MMGT1 MSMO1 MTIF3 NAPB PGRMC2 REEP4 RMDN3 SCN3B SLC10A6 SLC35H1 SLC71A2 SNAP23 SNAP25 SNAP29 STX1A STX2 STX4 STX5 STXBP1 STXBP2 SYT1 SYT4 SYT7 TBC1D30 TMEM14B TMPPE TMX2 TRPC3 TXLNA UBC VAMP3 VAMP7 VAMP8 ZDHHC15
Entrez ID		9066	6809
HPRD ID		11965	15985
Ensembl ID		ENSG00000011347	ENSG00000166900
Uniprot IDs		O43581	A0A286YF28 Q13277 Q53YE2
PDB IDs		2D8K	Not available
GO Terms Enriched among Interactors		SNAP Receptor Activity SNARE Complex SNARE Binding Vesicle Docking Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Neurotransmitter Transport Organelle Membrane Fusion Organelle Fusion Positive Regulation Of Synaptic Transmission Secretion By Cell Membrane Fusion Organelle Localization Exocytosis Secretion Membrane Assembly Intracellular Protein Transport Cornified Envelope Assembly Glutamatergic Synapse Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Endomembrane System Calcium-dependent Protein Binding Positive Regulation Of Protein Localization To Cell Periphery Membrane Organization Positive Regulation Of Protein Localization To Membrane Establishment Of Protein Localization Vesicle-mediated Transport In Synapse Vesicle Organization Schaffer Collateral - CA1 Synapse SNARE Complex Assembly Specific Granule Regulation Of Protein Localization To Plasma Membrane Cellular Localization Establishment Of Localization In Cell Vacuole Positive Regulation Of Protein Localization To Cell Surface Regulation Of Biological Quality Regulation Of Protein Localization To Cell Periphery Intracellular Protein Localization Modulation Of Chemical Synaptic Transmission Regulation Of Protein Localization To Membrane Presynaptic Active Zone Membrane Protein Transport Lamellipodium Positive Regulation Of Excitatory Postsynaptic Potential Vesicle-mediated Transport Intracellular Transport Synaptic Vesicle Endocytosis	Exocytosis SNARE Complex Secretion By Cell SNARE Binding Vesicle Fusion Syntaxin Binding Organelle Membrane Fusion Organelle Localization By Membrane Tethering SNAP Receptor Activity Secretion Membrane Docking Organelle Fusion Regulated Exocytosis Synaptic Vesicle Exocytosis Membrane Fusion Vesicle Docking Vesicle Organization Membrane Signal Release Calcium-ion Regulated Exocytosis Vesicle-mediated Transport Positive Regulation Of Regulated Secretory Pathway Vesicle-mediated Transport In Synapse Syntaxin-1 Binding Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Organelle Localization Regulation Of Regulated Secretory Pathway SNARE Complex Assembly Positive Regulation Of Exocytosis Regulation Of Exocytosis Neurotransmitter Transport Membrane Organization Regulation Of Vesicle Fusion Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Secretion By Cell Establishment Of Localization In Cell Vesicle Docking Involved In Exocytosis Regulation Of Secretion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Secretory Granule Regulation Of Vesicle-mediated Transport Synaptic Vesicle Membrane Organization Presynaptic Dense Core Vesicle Exocytosis Regulation Of Transport Regulation Of Calcium Ion-dependent Exocytosis Phagocytic Vesicle Membrane Synaptic Vesicle Priming Secretory Granule Localization