PPIE and XAB2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		PPIE	XAB2
Gene Name		peptidylprolyl isomerase E (cyclophilin E)	XPA binding protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Regulation Of Transcription, DNA-templated Protein Folding Positive Regulation Of Viral Genome Replication	MRNA Splicing, Via Spliceosome Blastocyst Development DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription, DNA-templated
Pathways			Nucleotide Excision Repair Transcription-coupled NER (TC-NER) Formation of transcription-coupled NER (TC-NER) repair complex Dual incision reaction in TC-NER
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: KMT2A PHYHIP XAB2	11 interactors: CACHD1 DHX16 ERCC6 ERCC8 GLIS2 ILF3 ISY1 POLR2A PPIE SMAD9 XPA
Entrez ID		10450	56949
HPRD ID		03893	18306
Ensembl ID		ENSG00000084072	ENSG00000076924
Uniprot IDs		Q9UNP9	Q9HCS7
PDB IDs		1ZMF 2CQB 2KU7 2KYX 2R99 3LPY 3MDF 3UCH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Response To Drug Regulation Of Histone H3-K14 Acetylation Regulation Of Cellular Response To Drug Regulation Of Response To Drug Regulation Of Histone H3-K9 Acetylation Histone H3-K4 Trimethylation Histone H4-K16 Acetylation Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H3-K4 Methylation DNA Metabolic Process Peptidyl-lysine Trimethylation Embryo Development Histone H3-K4 Methylation Embryonic Hemopoiesis Positive Regulation Of Histone Methylation Transcription-coupled Nucleotide-excision Repair Regulation Of Histone Acetylation Histone H4 Acetylation Regulation Of Histone Methylation Positive Regulation Of Transporter Activity DNA Methylation Positive Regulation Of Histone Modification Circadian Regulation Of Gene Expression DNA Modification Histone Lysine Methylation Nucleotide-excision Repair Peptidyl-lysine Methylation Blastocyst Development Transcription, DNA-templated Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Histone Methylation RNA Biosynthetic Process Internal Protein Amino Acid Acetylation Regulation Of Histone Modification Protein Acetylation Circadian Rhythm Protein Methylation See more	Nucleotide-excision Repair Nucleobase-containing Compound Metabolic Process Transcription-coupled Nucleotide-excision Repair Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nitrogen Compound Metabolic Process RNA Metabolic Process RNA Splicing Gene Expression Response To UV MRNA Processing Regulation Of Viral Process MRNA Metabolic Process Response To X-ray RNA Processing DNA Repair Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus Response To Light Stimulus Regulation Of Viral Genome Replication Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Viral Process DNA-templated Transcription, Elongation Response To Oxidative Stress Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Transcription, RNA-templated Response To Radiation DNA Metabolic Process Response To Abiotic Stimulus Multicellular Organism Growth Cellular Metabolic Process Response To Ionizing Radiation Positive Regulation Of Metabolic Process Response To Stress Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Response To Toxic Substance Intrinsic Apoptotic Signaling Pathway Mullerian Duct Regression Cellular Response To Stress Activation Of JNKK Activity Pyrimidine Dimer Repair Transcription From RNA Polymerase II Promoter See more
Tagcloud ?		archival arid1a barrett biopsies dysplasia eac enable endoscopic esophagus feasibility hgd illumina interactive libraries metaplasia missense mucosal ngs nonsense nse opportunity progressed progressor reiterating sanger scarce swi uncover unprecedented	aspect associates atra cockayne corepressor deacetylase defining dermatologic embryogenesis hl60 imr interfering lethality mol motifs neuroblastoma photoaging physiologic pigmentosum preimplantation preneoplastic promyelocytic raralpha retinoids rhabdomyosarcoma splicing tetratricopeptide xeroderma xpa
Tagcloud (Difference) ?		archival arid1a barrett biopsies dysplasia eac enable endoscopic esophagus feasibility hgd illumina interactive libraries metaplasia missense mucosal ngs nonsense nse opportunity progressed progressor reiterating sanger scarce swi uncover unprecedented	aspect associates atra cockayne corepressor deacetylase defining dermatologic embryogenesis hl60 imr interfering lethality mol motifs neuroblastoma photoaging physiologic pigmentosum preimplantation preneoplastic promyelocytic raralpha retinoids rhabdomyosarcoma splicing tetratricopeptide xeroderma xpa
Tagcloud (Intersection) ?