PPIE and SLU7

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		PPIE	SLU7
Description		peptidylprolyl isomerase E	spliceosome associated SLU7
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GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Nuclear Speck Protein-containing Complex Secretory Granule Lumen Intracellular Membrane-bounded Organelle U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Ficolin-1-rich Granule Lumen	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Membrane Nuclear Speck Small Nuclear Ribonucleoprotein Complex Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Poly(A) Binding Cyclosporin A Binding Isomerase Activity	Second Spliceosomal Transesterification Activity Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of DNA-templated Transcription MRNA Processing Protein Folding RNA Splicing Positive Regulation Of Viral Genome Replication	RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing Intracellular Protein Transport RNA Splicing Cellular Response To Heat
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Neutrophil degranulation mRNA Splicing - Major Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Asthma ( 32296059) Common carotid intima-media thickness ( 29206233)
Interacting Genes		11 interacting genes: GTSE1 KMT2A PCM1 PHYHIP PRC1 PRPF6 SLU7 SUMO2 TRIM55 TRIM63 XAB2	29 interacting genes: AIMP2 BAG2 CCDC85B CEP70 DEF6 FHL3 GOLGA2 GTF2I HNRNPA0 IKBKG JMJD6 KDM1A KRT40 LMNA LONRF1 LZTS2 MCC NFKBID NSD3 PCBP2 PIBF1 PPIE PPIG PPIL3 PRMT5 PRMT6 TEPSIN THAP1 ZCCHC10
Entrez ID		10450	10569
HPRD ID		03893	12074
Ensembl ID		ENSG00000084072	ENSG00000164609
Uniprot IDs		E9PK21 Q9UNP9	O95391
PDB IDs		1ZMF 2CQB 2KU7 2KYX 2R99 3LPY 3MDF 3UCH 5MQF 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 7A5P 7ABI 7W59 7W5A 7W5B 7ZEV 7ZEW 7ZEX 7ZEY 7ZEZ 8C6J 8CH6 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 9FMD	5XJC 6ICZ 6QDV 7W5A 7W5B 8C6J 9FMD
Enriched GO Terms of Interacting Partners?		Catalytic Step 2 Spliceosome Microtubule MRNA Splicing, Via Spliceosome Spliceosomal Complex Protein-RNA Complex Assembly RNA Splicing, Via Transesterification Reactions Microtubule Cytoskeleton Second Spliceosomal Transesterification Activity Negative Regulation Of DNA Methylation-dependent Heterochromatin Formation Protein-cysteine Methyltransferase Activity Protein-containing Complex Localization To Centriolar Satellite Mitotic Spindle Elongation Generation Of Catalytic Spliceosome For First Transesterification Step Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Nucleoplasm	Nucleoplasm Peptidyl-prolyl Cis-trans Isomerase Activity Histone Methyltransferase Activity Histone H4R3 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone Arginine N-methyltransferase Activity Protein Demethylase Activity Cyclosporin A Binding Protein-arginine N-methyltransferase Activity Golgi Ribbon Formation Transcription Regulator Activator Activity Protein Binding Nucleus Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Chromatin Organization Protein Folding Histone Demethylase Activity Regulation Of Macromolecule Metabolic Process Regulation Of Protein Modification Process Chromatin Remodeling Histone Methyltransferase Complex Regulation Of Gene Expression Cytoskeleton Organization Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Regulation Of Signal Transduction By P53 Class Mediator Histone H4R3 Demethylase Activity Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Peptidyl-lysine 5-dioxygenase Activity Histone H3R2 Demethylase Activity Oxidative RNA Demethylation Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity Histone H2AR3 Methyltransferase Activity Primary Ureteric Bud Growth Coated Vesicle Membrane Positive Regulation Of Macromolecule Metabolic Process
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