PPIE and PHYHIP

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PPIE	PHYHIP
Gene Name		peptidylprolyl isomerase E (cyclophilin E)	phytanoyl-CoA 2-hydroxylase interacting protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Regulation Of Transcription, DNA-templated Protein Folding Positive Regulation Of Viral Genome Replication
Pathways
Drugs
Diseases
GWAS			Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		3 interactors: KMT2A PHYHIP XAB2	24 interactors: BAI1 C14orf1 COPS6 DYRK1A EEF1A1 FAM131A HDAC11 HNRNPA1 MAGED4B MED8 METTL18 NDRG1 NDUFV3 NFE2 PHYH PNPLA2 PPIE PRMT5 S100A13 SMARCC2 SUPT5H TTR WDR89 ZZEF1
Entrez ID		10450	9796
HPRD ID		03893	16345
Ensembl ID		ENSG00000084072	ENSG00000168490
Uniprot IDs		Q9UNP9	Q92561
PDB IDs		1ZMF 2CQB 2KU7 2KYX 2R99 3LPY 3MDF 3UCH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Response To Drug Regulation Of Histone H3-K14 Acetylation Regulation Of Cellular Response To Drug Regulation Of Response To Drug Regulation Of Histone H3-K9 Acetylation Histone H3-K4 Trimethylation Histone H4-K16 Acetylation Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H3-K4 Methylation DNA Metabolic Process Peptidyl-lysine Trimethylation Embryo Development Histone H3-K4 Methylation Embryonic Hemopoiesis Positive Regulation Of Histone Methylation Transcription-coupled Nucleotide-excision Repair Regulation Of Histone Acetylation Histone H4 Acetylation Regulation Of Histone Methylation Positive Regulation Of Transporter Activity DNA Methylation Positive Regulation Of Histone Modification Circadian Regulation Of Gene Expression DNA Modification Histone Lysine Methylation Nucleotide-excision Repair Peptidyl-lysine Methylation Blastocyst Development Transcription, DNA-templated Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Histone Methylation RNA Biosynthetic Process Internal Protein Amino Acid Acetylation Regulation Of Histone Modification Protein Acetylation Circadian Rhythm Protein Methylation	Nucleosome Disassembly Chromatin Organization Mast Cell Activation MRNA Processing RNA Metabolic Process Cellular Metabolic Process MRNA Metabolic Process MRNA Splicing, Via Spliceosome Interleukin-1 Alpha Secretion RNA Splicing, Via Transesterification Reactions Gene Expression RNA Processing Chromosome Organization Chromatin Modification Positive Regulation Of Viral Process Nucleobase-containing Compound Metabolic Process Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Methyl-branched Fatty Acid Metabolic Process Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Glial Cell Development Peripheral Nervous System Development Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Acylglycerol Acyl-chain Remodeling Thyroid Hormone Transport Isoprenoid Metabolic Process Fatty Acid Alpha-oxidation Interleukin-1 Secretion Positive Regulation Of Spindle Checkpoint Regulation Of RNA Metabolic Process
Tagcloud ?		archival arid1a barrett biopsies dysplasia eac enable endoscopic esophagus feasibility hgd illumina interactive libraries metaplasia missense mucosal ngs nonsense nse opportunity progressed progressor reiterating sanger scarce swi uncover unprecedented
Tagcloud (Difference) ?		archival arid1a barrett biopsies dysplasia eac enable endoscopic esophagus feasibility hgd illumina interactive libraries metaplasia missense mucosal ngs nonsense nse opportunity progressed progressor reiterating sanger scarce swi uncover unprecedented
Tagcloud (Intersection) ?