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ARIH2 and UBE2R2
Number of citations of the paper that reports this interaction (PMID
19549727
)
40
Data Source:
BioGRID
(two hybrid)
ARIH2
UBE2R2
Gene Name
ariadne RBR E3 ubiquitin protein ligase 2
ubiquitin-conjugating enzyme E2R 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cytoplasm
Molecular Function
Nucleic Acid Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin-protein Transferase Activity
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Protein Polyubiquitination
Multicellular Organismal Development
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Developmental Cell Growth
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Hematopoietic Stem Cell Proliferation
Protein Monoubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
44 interactors:
ARAP1
BUB1
CBR3
CCDC33
CUL5
DISC1
DLST
EEF1A1
EEF1G
EML4
ENSA
IL4R
KAT5
KCNQ2
KIAA1377
LOC147791
NEDD8
PHF7
PPP2R1A
PTN
REL
RHEB
RPL8
SCAMP2
SGCE
SLC1A6
TP53
TRIM27
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2L3
UBE2L6
UBE2N
UBE2R2
UBE2T
UBE2V1
UGP2
UTP14A
WDR91
17 interactors:
APPBP2
ARHGDIA
ARIH2
BTRC
CBLC
CSNK2A1
CSNK2A2
DTX3L
DZIP3
FBXW5
INF2
MEOX1
PNPLA2
RBX1
RNF113B
UBA1
UBC
Entrez ID
10425
54926
HPRD ID
09286
15602
Ensembl ID
ENSG00000177479
ENSG00000107341
Uniprot IDs
O95376
Q6IBL8
Q712K3
PDB IDs
Enriched GO Terms of Interacting Partners
?
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Protein K63-linked Ubiquitination
Protein K11-linked Ubiquitination
Modification-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Cell Cycle Process
ISG15-protein Conjugation
Catabolic Process
Cellular Protein Metabolic Process
Cellular Protein Modification Process
Toll-like Receptor 4 Signaling Pathway
Protein Monoubiquitination
Cell Cycle
Toll-like Receptor Signaling Pathway
Mitotic Cell Cycle Process
Pattern Recognition Receptor Signaling Pathway
Mitotic Cell Cycle
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Protein Ubiquitination
Activation Of Innate Immune Response
Cellular Response To Organic Substance
Response To Organic Substance
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Protein Metabolic Process
Positive Regulation Of Innate Immune Response
Regulation Of Ubiquitin-protein Transferase Activity
Cellular Response To Stimulus
Response To Stimulus
Regulation Of Chromosome Organization
Regulation Of Protein Ubiquitination
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Proteolysis
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Mitotic Spindle Assembly Checkpoint
Regulation Of Mitotic Cell Cycle Phase Transition
Spindle Assembly Checkpoint
Mitotic Spindle Checkpoint
Immune Response
Regulation Of Cell Cycle Phase Transition
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Modification Process
Cellular Macromolecule Catabolic Process
Protein Polyubiquitination
Catabolic Process
Cellular Protein Metabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Proteolysis
Mitotic Cell Cycle Process
Mitotic Cell Cycle
Regulation Of Protein Catabolic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Protein Metabolic Process
Mitotic Cell Cycle Checkpoint
Regulation Of Proteasomal Protein Catabolic Process
Mitotic Spindle Checkpoint
Protein Monoubiquitination
Negative Regulation Of Chromosome Segregation
Positive Regulation Of Protein Catabolic Process
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cell Cycle Process
Regulation Of Cell Cycle Phase Transition
Cell Cycle Checkpoint
Spindle Checkpoint
Regulation Of Mitotic Sister Chromatid Separation
Negative Regulation Of Mitotic Nuclear Division
Negative Regulation Of ERBB Signaling Pathway
Regulation Of Mitotic Metaphase/anaphase Transition
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Wnt Signaling Pathway
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteolysis
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Wnt Signaling Pathway
Rhythmic Process
Tagcloud
?
aldo1
anxa2
cdna
cerebral
characterize
coding
cortical
ddit3
egr1
endoplasmic
ero1l
fold
gadd153
gas5
giig11
gpi1
hig1
hypoxia
microarray
ndr1
neuronal
p4hb
profiling
reinforce
repressed
reticulum
sac1p
ubiquitination
vdac2
Tagcloud (Difference)
?
aldo1
anxa2
cdna
cerebral
characterize
coding
cortical
ddit3
egr1
endoplasmic
ero1l
fold
gadd153
gas5
giig11
gpi1
hig1
hypoxia
microarray
ndr1
neuronal
p4hb
profiling
reinforce
repressed
reticulum
sac1p
ubiquitination
vdac2
Tagcloud (Intersection)
?