VENTX and TBX15

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		VENTX	TBX15
Gene Name		VENT homeobox	T-box 15
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Tle3-Aes Complex
	Molecular Function	Sequence-specific DNA Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Corepressor Activity Sequence-specific DNA Binding Transcription Factor Activity Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription, DNA-templated Multicellular Organismal Development	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Embryonic Cranial Skeleton Morphogenesis
Pathways
Drugs
Diseases
GWAS			Congenital heart malformation ( 23708190) Waist-hip ratio ( 20935629)
Protein-Protein Interactions		10 interactors: C1orf94 DAB1 IRF9 KRTAP12-2 KRTAP12-4 RBPMS TBX15 TBX22 TLE1 TLE2	3 interactors: ATXN1 POLE2 VENTX
Entrez ID		27287	6913
HPRD ID		06197	16035
Ensembl ID		ENSG00000151650	ENSG00000092607
Uniprot IDs		O95231	Q8N8P2 Q96SF7
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cerebellum Structural Organization Notch Signaling Pathway Lateral Motor Column Neuron Migration Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Spinal Cord Motor Neuron Migration Negative Regulation Of Wnt Signaling Pathway Radial Glia Guided Migration Of Purkinje Cell Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Organ Morphogenesis Wnt Signaling Pathway Negative Regulation Of Signal Transduction Anatomical Structure Morphogenesis Type I Interferon Biosynthetic Process Regulation Of Wnt Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of SMAD Protein Import Into Nucleus Golgi Localization Negative Regulation Of Anoikis Multicellular Organismal Development Type I Interferon Production Negative Regulation Of Astrocyte Differentiation Regulation Of Signal Transduction Regulation Of SMAD Protein Import Into Nucleus Regulation Of Anoikis	Error-prone Translesion Synthesis Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Translesion Synthesis Nucleotide-excision Repair, DNA Gap Filling Telomere Maintenance Via Semi-conservative Replication Postreplication Repair Nuclear DNA Replication Telomere Maintenance Via Recombination Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Mitotic Recombination Telomere Maintenance Via Telomere Lengthening DNA Replication Initiation
Tagcloud ?		challenge clonogenicity engraftment ex expansion helped hematopoietic homeobox hsc il2rgamma2 implicated intensive intrinsic investigations mechanistically mpp mpps multipotent nevertheless null ontogenesis pools preserve progenitor regulators scid strikingly suppression wnt
Tagcloud (Difference) ?		challenge clonogenicity engraftment ex expansion helped hematopoietic homeobox hsc il2rgamma2 implicated intensive intrinsic investigations mechanistically mpp mpps multipotent nevertheless null ontogenesis pools preserve progenitor regulators scid strikingly suppression wnt
Tagcloud (Intersection) ?