HMG20B and CCDC136

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HMG20B	CCDC136
Gene Name		high mobility group 20B	coiled-coil domain containing 136
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Chromosome	Mitochondrion Integral Component Of Membrane
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Blood Coagulation Negative Regulation Of Protein Sumoylation Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: APP BRCA2 CCDC102B CCDC136 CCDC85B HNRNPL KIF4A KRT15 KRT38 NKX3-1 PHF21A SYCE1 TACC2 TFIP11 VIM	62 interactors: ABT1 AQP1 ASB7 ATP5O ATXN1 BARD1 BLOC1S6 BYSL C19orf66 C1orf216 CBX8 CCDC146 CCHCR1 CDC5L CDK2AP1 CEP57L1 COIL CWF19L2 DISC1 ENKD1 FAM107A FAM161A GFI1B HAUS1 HDAC4 HMG20A HMG20B JMY KANSL1 KAT5 KIFC3 LENG1 MAGEB4 MOS NDN NEBL PDLIM5 PKN2 PPP1R18 PRPF31 PSMD9 RAB33A SMARCE1 TBRG1 TCEA2 TNNT1 TXLNA UBQLN4 USP2 ZBTB38 ZC2HC1C ZNF20 ZNF230 ZNF250 ZNF408 ZNF417 ZNF490 ZNF564 ZNF572 ZNF581 ZNF587 ZSCAN26
Entrez ID		10362	64753
HPRD ID		05703	10887
Ensembl ID		ENSG00000064961	ENSG00000128596
Uniprot IDs		Q9P0W2	Q96JN2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mitotic Cell Cycle Suckling Behavior Cell Cycle Process Developmental Process Axon Cargo Transport Cell Cycle Positive Regulation Of Cell Cycle Microtubule-based Process Spliceosomal Complex Disassembly Anatomical Structure Development Regulation Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction Positive Regulation Of Androgen Secretion Apoptotic Process Feeding Behavior Central Nervous System Development MRNA Processing Blood Coagulation Cell Division Hemostasis Programmed Cell Death Microtubule Cytoskeleton Organization Meiosis I Cytokinesis Cell Death Death Collateral Sprouting In Absence Of Injury Negative Regulation Of Estrogen Receptor Binding System Development Cytoskeleton Organization Organ Development Spindle Organization Negative Regulation Of Epithelial Cell Proliferation Microtubule-based Transport MRNA Metabolic Process Cytoskeleton-dependent Intracellular Transport Organelle Organization Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Binding Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Peptidase Activity Cell Maturation RNA Processing RNA Metabolic Process Regulation Of Body Fluid Levels Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Wound Healing Nucleobase-containing Compound Metabolic Process	Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Gene Expression Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Biosynthetic Process Chromatin Organization Chromatin Modification Cellular Metabolic Process Organelle Organization Cell Cycle Regulation Of Cellular Process Chromosome Organization Negative Regulation Of Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Chromatin Remodeling Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Protein Sumoylation Regulation Of Cell Cycle Signal Transduction In Response To DNA Damage Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Catabolic Process Signal Transduction By P53 Class Mediator Negative Regulation Of Biosynthetic Process Regulation Of Protein Metabolic Process Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Maintenance Of Symbiont-containing Vacuole By Host 'de Novo' Actin Filament Nucleation Transepithelial Water Transport Cardiac Muscle Thin Filament Assembly
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