HMG20B and TACC2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HMG20B	TACC2
Gene Name		high mobility group 20B	transforming, acidic coiled-coil containing protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Chromosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Microtubule Organizing Center Microtubule Cytoskeleton
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Protein Heterodimerization Activity	Protein Domain Specific Binding Nuclear Hormone Receptor Binding
	Biological Process	Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Blood Coagulation Negative Regulation Of Protein Sumoylation Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation	Microtubule Cytoskeleton Organization Cell Proliferation Cerebral Cortex Development Neurogenesis Interkinetic Nuclear Migration Astral Microtubule Organization Regulation Of Microtubule-based Process
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Myopia (pathological) ( 23049088) Obesity-related traits ( 23251661)
Protein-Protein Interactions		15 interactors: APP BRCA2 CCDC102B CCDC136 CCDC85B HNRNPL KIF4A KRT15 KRT38 NKX3-1 PHF21A SYCE1 TACC2 TFIP11 VIM	11 interactors: AURKC CREBBP EP300 HMG20B KAT2A KAT2B PPP1CC RXRB SMARCB1 UBC YEATS4
Entrez ID		10362	10579
HPRD ID		05703	05600
Ensembl ID		ENSG00000064961	ENSG00000138162
Uniprot IDs		Q9P0W2	D6RAA5 E7EMZ9 E9PBC6 O95359 Q4VXL8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mitotic Cell Cycle Suckling Behavior Cell Cycle Process Developmental Process Axon Cargo Transport Cell Cycle Positive Regulation Of Cell Cycle Microtubule-based Process Spliceosomal Complex Disassembly Anatomical Structure Development Regulation Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction Positive Regulation Of Androgen Secretion Apoptotic Process Feeding Behavior Central Nervous System Development MRNA Processing Blood Coagulation Cell Division Hemostasis Programmed Cell Death Microtubule Cytoskeleton Organization Meiosis I Cytokinesis Cell Death Death Collateral Sprouting In Absence Of Injury Negative Regulation Of Estrogen Receptor Binding System Development Cytoskeleton Organization Organ Development Spindle Organization Negative Regulation Of Epithelial Cell Proliferation Microtubule-based Transport MRNA Metabolic Process Cytoskeleton-dependent Intracellular Transport Organelle Organization Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Binding Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Peptidase Activity Cell Maturation RNA Processing RNA Metabolic Process Regulation Of Body Fluid Levels Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Wound Healing Nucleobase-containing Compound Metabolic Process	Chromatin Modification N-terminal Peptidyl-lysine Acetylation Chromatin Organization Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Chromosome Organization Protein Acetylation Histone Modification Positive Regulation Of Transcription, DNA-templated N-terminal Protein Amino Acid Acetylation Cell Cycle Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Peptidyl-lysine Modification Viral Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Rhythmic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia N-terminal Protein Amino Acid Modification Notch Signaling Pathway Mitotic Cell Cycle RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Chromatin Remodeling Gene Expression Regulation Of Gene Expression Peptidyl-amino Acid Modification Histone H4 Acetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cellular Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription In Response To Stress Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Gluconeogenesis By Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Cell Cycle Process Regulation Of Cellular Ketone Metabolic Process By Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Type I Interferon Production Mitotic Cell Cycle Process Regulation Of Transcription, DNA-templated Positive Regulation By Host Of Viral Transcription Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process
Tagcloud ?			abundantly affymetrix annotated ccnd1 crmp1 curing cycles ddc endpoint gabrb3 hurdle hydroxylase immunotherapy isl1 kif1a marrows mrd neuroblastoma phox2b prioritize profiling ranking sampled serves stringent surrogate top u95 uncover
Tagcloud (Difference) ?			abundantly affymetrix annotated ccnd1 crmp1 curing cycles ddc endpoint gabrb3 hurdle hydroxylase immunotherapy isl1 kif1a marrows mrd neuroblastoma phox2b prioritize profiling ranking sampled serves stringent surrogate top u95 uncover
Tagcloud (Intersection) ?