HMG20B and ERP29

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HMG20B	ERP29
Description		high mobility group 20B	endoplasmic reticulum protein 29
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nuclear Body	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Cell Surface Membrane Melanosome
	Molecular Function	DNA Binding Protein Binding	Protein Disulfide Isomerase Activity Protein Binding Protein Homodimerization Activity Protein-folding Chaperone Binding
	Biological Process	Chromatin Organization Regulation Of Gene Expression Protein Sumoylation Negative Regulation Of Protein Sumoylation Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation	Protein Folding Intracellular Protein Transport Protein Secretion Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Protein Unfolding Positive Regulation Of MAPK Cascade Negative Regulation Of Protein Secretion Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways		HDACs deacetylate histones Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823)	Body mass index ( 26426971) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		27 interacting genes: APP BRCA2 C14orf119 CCDC102B CCDC136 CCDC85B E2F6 ERP29 FBXO7 HNRNPL KIF4A KRT15 KRT38 MID1 NKX3-1 NUTF2 PHF21A PIAS2 PPP1R13B SNAPC5 SYCE1 TACC2 TFIP11 TRAF1 USHBP1 VIM WAC	21 interacting genes: ADIPOQ BMP10 C3orf52 CEBPA CTNNBL1 DESI1 GLP1R HMG20B HSPA5 NRM PUF60 SGTA SGTB SLC35B4 SLC38A7 TMBIM6 TMEM86B TSPO2 UBQLN1 UBQLN2 UBQLN4
Entrez ID		10362	10961
HPRD ID		05703	03794
Ensembl ID		ENSG00000064961	ENSG00000089248
Uniprot IDs		Q9P0W2	P30040 V9HW71
PDB IDs			2QC7 5V8Z 5V90
Enriched GO Terms of Interacting Partners?			Regulation Of Proteasomal Protein Catabolic Process Regulation Of Response To Endoplasmic Reticulum Stress TRC Complex Positive Regulation Of ERAD Pathway Regulation Of Protein Catabolic Process Regulation Of Proteolysis ERAD Pathway Regulation Of ERAD Pathway Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteasomal Protein Catabolic Process Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Identical Protein Binding Negative Regulation Of IRE1-mediated Unfolded Protein Response Negative Regulation Of Response To Endoplasmic Reticulum Stress Post-translational Protein Targeting To Membrane, Translocation Regulation Of Cellular Response To Stress Regulation Of Protein Metabolic Process Endoplasmic Reticulum Regulation Of Ubiquitin-dependent Protein Catabolic Process IRE1-mediated Unfolded Protein Response Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Autophagosome Regulation Of IRE1-mediated Unfolded Protein Response Protein-containing Complex Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Cellular Localization Positive Regulation Of Protein Metabolic Process Autophagy Brown Fat Cell Differentiation Protein Targeting To ER Intracellular Protein Transmembrane Transport Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Receptor-mediated Endocytosis Establishment Of Protein Localization To Endoplasmic Reticulum RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Integrated Stress Response Signaling Glucagon-like Peptide 1 Receptor Activity Regulation Of Endoplasmic Reticulum Unfolded Protein Response Regulation Of Protein Folding In Endoplasmic Reticulum Negative Regulation Of Calcium Ion Transmembrane Transport Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Positive Regulation Of Glycogen (starch) Synthase Activity Negative Regulation Of Store-operated Calcium Channel Activity
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