HMG20B and KIF4A

Number of citations of the paper that reports this interaction (PubMedID 12809554)
25

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		HMG20B	KIF4A
Description		high mobility group 20B	kinesin family member 4A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nuclear Body	Nucleus Chromosome Cytoplasm Spindle Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Spindle Microtubule Membrane Nuclear Matrix Midbody Axon Cytoplasm
	Molecular Function	DNA Binding Protein Binding	Nucleotide Binding DNA Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Metal Ion Binding Iron-sulfur Cluster Binding
	Biological Process	Chromatin Organization Regulation Of Gene Expression Protein Sumoylation Negative Regulation Of Protein Sumoylation Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation	Mitotic Cytokinesis Organelle Organization Microtubule-based Movement Mitotic Spindle Organization Anterograde Axonal Transport Spindle Elongation Mitotic Spindle Midzone Assembly
Pathways		HDACs deacetylate histones Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production	MHC class II antigen presentation Recycling pathway of L1 Recycling pathway of L1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823)
Interacting Genes		27 interacting genes: APP BRCA2 C14orf119 CCDC102B CCDC136 CCDC85B E2F6 ERP29 FBXO7 HNRNPL KIF4A KRT15 KRT38 MID1 NKX3-1 NUTF2 PHF21A PIAS2 PPP1R13B SNAPC5 SYCE1 TACC2 TFIP11 TRAF1 USHBP1 VIM WAC	7 interacting genes: APP CEBPA DNMT3B HMG20B PRC1 SUMO2 TTF2
Entrez ID		10362	24137
HPRD ID		05703	06606
Ensembl ID		ENSG00000064961	ENSG00000090889
Uniprot IDs		Q9P0W2	O95239 Q59HG1
PDB IDs			6OYL
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Regulation Of Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Presynapse DNA Binding Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Protein Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Protein Metabolic Process Positive Regulation Of Toll Signaling Pathway RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding DNA (cytosine-5-)-methyltransferase Activity, Acting On CpG Substrates Protein Sumoylation Positive Regulation Of Androgen Receptor Signaling Pathway Protein Heterodimerization Activity Positive Regulation Of DNA-templated Transcription Initiation Acetylcholine Receptor Activator Activity Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Differentiation Lipoprotein Particle Positive Regulation Of Protein Import Regulation Of DNA-templated Transcription Initiation Response To Vitamin B2 C/EBP Complex Negative Regulation Of Post-translational Protein Modification Negative Regulation Of Protein Autoubiquitination Mitotic Spindle Elongation PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Cell Cycle CHOP-C/EBP Complex
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