CCDC136 and ZNF417

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		CCDC136	ZNF417
Description		coiled-coil domain containing 136	zinc finger protein 417
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Membrane Cytoplasmic Vesicle	Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Acrosome Assembly Spermatogenesis Single Fertilization Cell Differentiation	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hypertrophic cardiomyopathy ( 33495596) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)	Depression in smokers ( 30219690)
Interacting Genes		138 interacting genes: ABT1 AQP1 ATP5PO ATXN1 BARD1 BLOC1S6 BYSL C1orf216 C21orf58 CARD9 CBX8 CCDC120 CCDC13 CCDC146 CCDC185 CCDC187 CCDC6 CCHCR1 CDC5L CDK2AP1 CEP57 CEP57L1 CEP95 COIL CWF19L2 DDX6 DISC1 DTNB DYNC1I2 ENKD1 FAM107A FAM161A FAM161B FAM50B FLYWCH1 GFI1B HAUS1 HDAC4 HGS HMG20A HMG20B HOXB5 ISCU JAKMIP2 JMY JRK KANSL1 KAT5 KIF5B KIFC3 LCA5L LENG1 MAGEB4 MBD1 MBD3L2 MCRS1 MOS NDC80 NDN NEBL NEK6 NME7 NOP53 ODAD3 PDLIM5 PIBF1 PKN1 PKN2 POGZ PPP1R18 PRPF18 PRPF3 PRPF31 PRR35 PSMA1 PSMC5 PSMD9 RAB33A RAB33B RALBP1 RASAL3 RASSF8 SCNM1 SDHAF1 SHFL SMARCA2 SMARCE1 SYT6 TBRG1 TCEA2 TCEANC THAP7 TNNT1 TRAF3IP3 TSGA10 TSGA10IP TSPYL1 TXLNA UBQLN4 UBTFL1 USP2 WT1 ZBTB24 ZBTB38 ZBTB47 ZC2HC1C ZFP1 ZFYVE26 ZNF124 ZNF20 ZNF223 ZNF230 ZNF250 ZNF264 ZNF329 ZNF35 ZNF408 ZNF417 ZNF440 ZNF490 ZNF497 ZNF564 ZNF572 ZNF580 ZNF581 ZNF587 ZNF599 ZNF648 ZNF669 ZNF670 ZNF688 ZNF696 ZNF774 ZNF777 ZNF785 ZNF835 ZNF837 ZSCAN26	170 interacting genes: - ADAMTSL4 AXIN2 BEGAIN BEND5 BEX3 BICD2 C4orf17 CARD9 CBY2 CCDC125 CCDC136 CCDC57 CCDC85B CCNDBP1 CDR2 CDR2L CEP44 CEP70 CEP72 CEP85L CHRDL2 COG6 CSRNP1 CYSRT1 DEF8 DVL3 EFS EZHIP FAM221A FHL2 FHL3 FHL5 FRS3 FSD2 FXR1 GOLGA2 GOLGA6L9 GPRASP3 HMBOX1 HOMEZ HOOK2 HOXA1 HSF2BP IGFBP6 IHO1 IKZF1 INKA1 JADE2 JRK KAT5 KATNBL1 KCTD7 KIF9 KIFC3 KLC3 KRT15 KRT31 KRT35 KRT38 KRT39 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-9 KXD1 LHX3 LIMS1 LMO1 LURAP1 LZTS1 LZTS2 MAGEA8 MAST2 MCC MCCD1 MDFI MEIS3 MEOX2 MID2 MIIP MRFAP1L1 MTUS2 MYF5 MYLIP NAB2 NBPF19 NDEL1 NDUFB7 NINL NKAPL NKX3-1 NOTCH2NLA OIP5 PHC2 PICK1 PIH1D2 PLSCR1 PNMA2 PRICKLE4 PRPF31 RCN3 REL RHOQ RNF187 RORB RPGRIP1 RUNDC3A SH2B2 SMARCD1 SMYD5 SPRED1 SPRED2 SPRY1 SPRY2 SSX2IP STX11 SUV39H1 TADA2A TCF4 TEKT4 TFIP11 TLE5 TMCC2 TNS2 TRAF1 TRAF2 TRIB3 TRIM23 TRIM27 TRIM36 TRIM37 TRIM41 TRIM54 TSC1 TSGA10 TXNDC11 U2AF1 USHBP1 VPS16 VPS52 VWC2 ZBTB1 ZBTB10 ZBTB43 ZBTB8A ZBTB9 ZNF165 ZNF19 ZNF20 ZNF547 ZNF572 ZNF587 ZNF69 ZNF71 ZNF768 ZNF774 ZNF837 ZNF85 ZRANB1
Entrez ID		64753	147687
HPRD ID		10887	18341
Ensembl ID		ENSG00000128596	ENSG00000173480
Uniprot IDs		C9JU31 Q96JN2	M0R230 Q8TAU3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Zinc Ion Binding Regulation Of RNA Metabolic Process DNA Binding Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Centrosome Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Metal Ion Binding Regulation Of Metabolic Process Cytoskeleton Chromatin Organization Microtubule-based Process Cilium Organization Nuclear Speck Microtubule Binding Spindle Pole Organelle Assembly Nuclear Proteasome Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Identical Protein Binding Nucleoplasm Regulation Of Sister Chromatid Segregation Cellular Component Assembly Microtubule Cytoskeleton Organization DNA-binding Transcription Factor Activity Centriole Protein Localization To Nucleoplasm Establishment Of Spindle Orientation Microtubule Double-stranded Methylated DNA Binding Cytosolic Proteasome Complex Centriolar Satellite Regulation Of Chromosome Segregation Regulation Of Protein Sumoylation Non-motile Cilium Assembly Histone Acetyltransferase Complex Ciliary Basal Body Establishment Of Spindle Localization	Keratin Filament Intermediate Filament Protein Binding Identical Protein Binding Zinc Ion Binding Negative Regulation Of Lens Fiber Cell Differentiation Regulation Of Lens Fiber Cell Differentiation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Structural Constituent Of Skin Epidermis Cytoskeleton Protein Serine/threonine Kinase Inhibitor Activity Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Microtubule Binding Cytoskeleton Organization Microtubule-based Process Regulation Of Nucleobase-containing Compound Metabolic Process Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Microtubule DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Organelle Organization Hair Cycle Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Stem Cell Factor Receptor Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?