CCDC136 and CEP57L1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CCDC136	CEP57L1
Gene Name		coiled-coil domain containing 136	centrosomal protein 57kDa-like 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Integral Component Of Membrane	Cellular_component Cytoplasm Microtubule Organizing Center Microtubule
	Molecular Function		Molecular_function Microtubule Binding Identical Protein Binding Gamma-tubulin Binding
	Biological Process		Biological_process Microtubule Anchoring
Pathways
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		62 interactors: ABT1 AQP1 ASB7 ATP5O ATXN1 BARD1 BLOC1S6 BYSL C19orf66 C1orf216 CBX8 CCDC146 CCHCR1 CDC5L CDK2AP1 CEP57L1 COIL CWF19L2 DISC1 ENKD1 FAM107A FAM161A GFI1B HAUS1 HDAC4 HMG20A HMG20B JMY KANSL1 KAT5 KIFC3 LENG1 MAGEB4 MOS NDN NEBL PDLIM5 PKN2 PPP1R18 PRPF31 PSMD9 RAB33A SMARCE1 TBRG1 TCEA2 TNNT1 TXLNA UBQLN4 USP2 ZBTB38 ZC2HC1C ZNF20 ZNF230 ZNF250 ZNF408 ZNF417 ZNF490 ZNF564 ZNF572 ZNF581 ZNF587 ZSCAN26	69 interactors: ALOX5 AP1M1 ARNT2 BRCA1 BYSL C6orf165 CALCOCO2 CARD9 CCDC102B CCDC136 CCDC57 CDR2 CEP44 CEP55 CEP63 CEP70 DISC1 DYDC1 EXOC8 FAM161A FAM9B GADD45G GOLGA1 GOLGA2 HAUS1 HDDC3 HGS IKZF1 KATNAL1 KIFC3 KLC3 KLC4 KRT13 KRT19 KRT31 KRT38 KRT40 LENG1 LMO3 LZTS2 MAGEA1 MAGEA2B MDFI MEOX2 MFAP1 MID2 MORF4L1 MTUS2 MYO15B NUP62 PKN1 PNMA5 PPL RAD51D RINT1 ROPN1 SNAP47 SNAPC3 SPERT TAB3 TCEB3 TFIP11 TRAF2 TRAPPC2L TRIM54 TRIP6 TSGA10 TXLNA TXLNB
Entrez ID		64753	285753
HPRD ID		10887	10792
Ensembl ID		ENSG00000128596	ENSG00000183137
Uniprot IDs		Q96JN2	G5E992 Q8IYX8
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Gene Expression Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Biosynthetic Process Chromatin Organization Chromatin Modification Cellular Metabolic Process Organelle Organization Cell Cycle Regulation Of Cellular Process Chromosome Organization Negative Regulation Of Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Chromatin Remodeling Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Protein Sumoylation Regulation Of Cell Cycle Signal Transduction In Response To DNA Damage Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Catabolic Process Signal Transduction By P53 Class Mediator Negative Regulation Of Biosynthetic Process Regulation Of Protein Metabolic Process Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Maintenance Of Symbiont-containing Vacuole By Host 'de Novo' Actin Filament Nucleation Transepithelial Water Transport Cardiac Muscle Thin Filament Assembly	Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of JNK Cascade Organelle Organization Microtubule-based Process Regulation Of Stress-activated MAPK Cascade Regulation Of MAPK Cascade Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Cell Cycle Regulation Of Signal Transduction Microtubule Severing Regulation Of Signaling I-kappaB Kinase/NF-kappaB Signaling Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Intracellular Signal Transduction Microtubule Cytoskeleton Organization Regulation Of MAP Kinase Activity Positive Regulation Of MAPK Cascade Positive Regulation Of JUN Kinase Activity Cellular Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Spindle Assembly Positive Regulation Of Protein Modification Process Regulation Of JUN Kinase Activity Double-strand Break Repair Via Homologous Recombination Recombinational Repair JNK Cascade Negative Regulation Of Protein Acetylation Centrosome Organization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of MAP Kinase Activity Mitotic Cell Cycle Positive Regulation Of Transferase Activity Microtubule Organizing Center Organization Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cell Cycle Process Cell Differentiation Involved In Embryonic Placenta Development Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Histone H4-K20 Methylation Leukotriene Production Involved In Inflammatory Response Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Spliceosomal Complex Disassembly Positive Regulation Of Histone H4-K16 Acetylation Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint
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