SEC24A and CBFA2T3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SEC24A	CBFA2T3
Gene Name		SEC24 family member A	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat Perinuclear Region Of Cytoplasm	Golgi Membrane Nucleus Nucleoplasm Nucleolus
	Molecular Function	Molecular_function Zinc Ion Binding	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Protein N-linked Glycosylation Via Asparagine Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-translational Protein Modification Cellular Protein Metabolic Process Small Molecule Metabolic Process Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process COPII Vesicle Coating Positive Regulation Of Protein Secretion Membrane Organization Positive Regulation Of Cholesterol Homeostasis	Transcription, DNA-templated Cell Proliferation Granulocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Diseases of glycosylation Metabolism of lipids and lipoproteins Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Antigen Presentation: Folding, assembly and peptide loading of class I MHC Defective MOGS causes MOGS-CDG (CDG-2b) Regulation of cholesterol biosynthesis by SREBP (SREBF) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 MHC class II antigen presentation Class I MHC mediated antigen processing & presentation COPII (Coat Protein 2) Mediated Vesicle Transport ER to Golgi Transport Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CBFA2T3 EWSR1 TFG TRIP13	14 interactors: CBFA2T2 GMEB2 HDAC1 HDAC3 MATN2 PRKAR2A RUNX1 RUNX1T1 SEC24A TCF3 ZBTB33 ZBTB38 ZBTB4 ZNF652
Entrez ID		10802	863
HPRD ID		08456	04847
Ensembl ID		ENSG00000113615	ENSG00000129993
Uniprot IDs		B4E205 O95486	O75081
PDB IDs		2NUP 2NUT 3EGD 3EGX
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Receptor Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Histone H4 Deacetylation Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Histone H3 Deacetylation Histone H3-K9 Modification Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Positive Regulation Of Cellular Metabolic Process Skin Development Response To Growth Factor Dendrite Regeneration Histone Deacetylation Protein Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Circadian Regulation Of Gene Expression Positive Regulation Of Progesterone Secretion Cellular Metabolic Process
Tagcloud ?		cargoes coated compensation considerably copii deficiency dispensable embryonic exhibiting fourth golgi haploinsufficient hepatocytes homozygous hypocholesterolemic lethality mammals nascent null paralog paralogs phenotypically tube vertebrate vesicles	7q amotl1 cn crebbp cul1 directory exome expanding expands fat4 fbxo11 flnc ighv1 integrating map3k14 minimally mll2 notch2 pla2g4d positioned recurrently silent smzl spen splenic tnfaip3 trrap ush2a wes
Tagcloud (Difference) ?		cargoes coated compensation considerably copii deficiency dispensable embryonic exhibiting fourth golgi haploinsufficient hepatocytes homozygous hypocholesterolemic lethality mammals nascent null paralog paralogs phenotypically tube vertebrate vesicles	7q amotl1 cn crebbp cul1 directory exome expanding expands fat4 fbxo11 flnc ighv1 integrating map3k14 minimally mll2 notch2 pla2g4d positioned recurrently silent smzl spen splenic tnfaip3 trrap ush2a wes
Tagcloud (Intersection) ?