BCAS2 and PRRC2B

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		BCAS2	PRRC2B
Description		BCAS2 pre-mRNA processing factor	proline rich coiled-coil 2B
Image			No pdb structure
GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm DNA Replication Factor A Complex Spliceosomal Complex Nucleolus Centrosome Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding	RNA Binding Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Ovarian Follicle Development MRNA Processing RNA Splicing Protein Catabolic Process Oogenesis Oocyte Development Spindle Assembly	Cell Differentiation
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Autism ( 24189344) Chronotype ( 30696823)	Femur bone mineral density x serum urate levels interaction ( 34046847) Lung function ( 31902109) Urate levels ( 31578528)
Interacting Genes		82 interacting genes: ACY1 AIMP2 ANKHD1 BLK CCDC120 CCDC17 CNOT4 CPSF7 DMRTB1 DUT ECM1 EIF4ENIF1 EMILIN3 ENKD1 EP300 ESR1 ESR2 FAM86C1P FHIT GOLGA2 HGS HNRNPLL HSF2BP IFI35 IKZF3 KRT20 KRT27 KRT31 KRT34 KRT35 KRT36 KRT37 KRT75 KRTAP19-6 KRTAP8-1 LARP4 LMO1 LMO2 LMO3 LMO4 MBNL1 MED29 MIIP MYOZ3 NIP7 OIP5 PAX5 PCBD2 PFDN5 PGR PLAGL2 PLEKHF2 POT1 PPARG PRRC2B QKI RBM22 RBPMS RPL5 SAXO4 SF1 SLAIN1 SMARCD1 SNRNP200 SNRPC SNW1 SPMIP5 SPMIP6 TCF4 TCHP TFIP11 TP53BP2 TRAF1 TRNAU1AP TXN2 TXNRD2 UBC USHBP1 WDR83 YPEL3 ZMAT5 ZWINT	41 interacting genes: ALG13 ANKHD1 APP ATN1 ATXN1 ATXN1L BAG4 BCAS2 CRK CTBP1 DAPK1 DDX11 DIMT1 DMRTB1 DNAJC5 DPY30 EHMT2 ESS2 EXOSC1 EXOSC4 EXOSC7 FBXO7 IPO5 LSM5 MRPL44 NIP7 NXF1 NXF5 PRPF39 QKI RBFOX2 RBPMS RERE RPL13 SF1 SRPK2 SRSF4 TRNAU1AP TXNL4A YTHDF1 YTHDF3
Entrez ID		10286	84726
HPRD ID		05777	13805
Ensembl ID		ENSG00000116752	ENSG00000288701
Uniprot IDs		B2R7W3 O75934	Q5JSZ5 Q9BU62
PDB IDs		5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P 7W59 7W5A 7W5B 8C6J 8CH6 8I0T 8I0U 8I0V 8I0W 8RO2 9FMD
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Organization Intermediate Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Protein Binding Nucleic Acid Binding MRNA Metabolic Process MRNA Processing Structural Molecule Activity Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Estrogen Response Element Binding RNA Binding RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Coregulator Binding RNA Processing Catalytic Step 2 Spliceosome Nucleus Positive Regulation Of Biosynthetic Process Transcription Coactivator Activity Nuclear Receptor Activity Nuclear Estrogen Receptor Activity TFIIB-class Transcription Factor Binding Nuclear Receptor-mediated Signaling Pathway Epithelial Cell Differentiation Nuclear Steroid Receptor Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Morphogenesis Of An Epithelium MRNA Binding DNA-binding Transcription Factor Binding Regulation Of RNA Splicing Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Protein-containing Complex Organization Steroid Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Cell Differentiation Supramolecular Fiber Organization Hormone-mediated Signaling Pathway Tissue Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization	RNA Binding Nucleus RNA Processing RNA Metabolic Process Nucleic Acid Binding RNA Splicing MRNA Metabolic Process Nucleolus MRNA Processing MRNA Binding Nucleoplasm Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Splicing, Via Transesterification Reactions Nucleolar Exosome (RNase Complex) Regulation Of MRNA Metabolic Process Cytoplasmic Stress Granule Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Macromolecule Metabolic Process Regulation Of RNA Splicing Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Regulation Of MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing POZ Domain Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Stress Granule Assembly Negative Regulation Of Macromolecule Metabolic Process MRNA Splice Site Recognition Exoribonuclease Complex Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Spliceosomal Complex Nuclear RNA Export Factor Complex U4 SnRNA 3'-end Processing Protein-RNA Complex Assembly Cytoplasm Transcription Corepressor Activity Negative Regulation Of Metabolic Process Spliceosomal Complex Assembly Memory Negative Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Nuclear MRNA Surveillance Nuclear Inclusion Body N6-methyladenosine-containing RNA Reader Activity
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