BCAS2 and SF1

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		BCAS2	SF1
Gene Name		breast carcinoma amplified sequence 2	splicing factor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm DNA Replication Factor A Complex Spliceosomal Complex Nucleolus Cell Junction	Nucleus Nucleoplasm Spliceosomal Complex Ribosome
	Molecular Function	Protein Binding	Transcription Corepressor Activity RNA Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated Male Sex Determination Leydig Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Urate levels ( 21768215)
Protein-Protein Interactions		18 interactors: AIMP2 BLK CDC5L EP300 ESR1 ESR2 GOLGA2 HGS IKZF3 KRT40 PGR POT1 PPARG PRPF19 SF1 TCF4 TXNRD2 UBC	45 interactors: APBB1 ATXN1 BCAS2 BCL2 CIAO1 DDX17 EFTUD2 ESR1 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MKRN3 NFKB1 PLSCR1 PNRC2 PRKG1 PRPF40A PSMA3 RBM10 RBM17 RBM4 RBM7 RBPMS SF3A1 SF3B4 TAF15 TCERG1 TRIM23 TRIM69 U2AF2 WBP4 WDR77 WDR83 WWP2 ZNF461
Entrez ID		10286	7536
HPRD ID		05777	03306
Ensembl ID		ENSG00000116752	ENSG00000168066
Uniprot IDs		B2R7W3 O75934	Q15637
PDB IDs			1K1G 1OPI 2M09 2M0G 4FXW 4FXX
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Regulation Of Cell Proliferation Hormone-mediated Signaling Pathway Rhythmic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Steroid Hormone Stimulus RNA Metabolic Process Gene Expression Positive Regulation Of Gene Expression Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Response To Steroid Hormone Ovulation Cycle Process Transcription, DNA-templated Tissue Development Reproductive Structure Development Reproductive System Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Female Gonad Development Biosynthetic Process Ovulation Cycle Transcription From RNA Polymerase II Promoter Development Of Primary Female Sexual Characteristics Regulation Of Transcription From RNA Polymerase II Promoter Sex Differentiation Cellular Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Response To Hormone Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Epithelium Development Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Organic Cyclic Compound Developmental Process Involved In Reproduction Cellular Response To Lipid Genitalia Development Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Negative Regulation Of Telomerase Activity Regulation Of Gene Expression	RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Metabolic Process Transcription, DNA-templated Regulation Of RNA Splicing RNA Biosynthetic Process Cellular Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Protein Ubiquitination Cellular Macromolecule Biosynthetic Process Response To Virus Positive Regulation Of Cellular Metabolic Process Protein Modification By Small Protein Conjugation Macromolecule Biosynthetic Process Defense Response To Virus Regulation Of MRNA Splicing, Via Spliceosome Protein Polyubiquitination Regulation Of Viral Genome Replication Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Process Positive Regulation Of Transcription, DNA-templated Regulation Of MRNA Processing Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Activation Apoptotic Process Response To Other Organism
Tagcloud ?		amplified ar assay carcinoma characterise characterised correlation degraded gst hsp90 immunohistochemical immunoprecipitation interacting lncap luciferase manners mtt p53 pca propose prostate proteasome pull regulator specimens stabilise stabilised suppressed upregulation	aaggtcagaaat aromatase belong br clones coup decided differently dnase ear encode err footprinting hybrid mobility ovary p120e4f promoters s1 shorter silencer situated sk specimen superfamily tf1 variant ws3tf
Tagcloud (Difference) ?		amplified ar assay carcinoma characterise characterised correlation degraded gst hsp90 immunohistochemical immunoprecipitation interacting lncap luciferase manners mtt p53 pca propose prostate proteasome pull regulator specimens stabilise stabilised suppressed upregulation	aaggtcagaaat aromatase belong br clones coup decided differently dnase ear encode err footprinting hybrid mobility ovary p120e4f promoters s1 shorter silencer situated sk specimen superfamily tf1 variant ws3tf
Tagcloud (Intersection) ?