- and EFHC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		-	EFHC2
Description		U2 small nuclear RNA auxiliary factor 1 like 5	EF-hand domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytoskeleton Microtubule Axonemal Microtubule Cilium Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath
	Molecular Function		Calcium Ion Binding Protein Binding
	Biological Process		Regulation Of Neuron Projection Development Flagellated Sperm Motility Cellular Response To Leukemia Inhibitory Factor
Pathways
Drugs
Diseases
GWAS		HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)	Body mass index and diastolic blood pressure (bivariate analysis) ( 33539483) Glaucoma (primary open-angle) ( 33627673) Mean arterial pressure ( 29403010)
Interacting Genes		16 interacting genes: AP1B1 AP2B1 CARNMT1 EFHC2 HMGB2 HNRNPK KRT1 KRT75 MEOX2 MLH1 SNRNP35 SRRM4 SRSF3 TRA2B U2AF2 ZNF417	100 interacting genes: - AASDHPPT ARHGEF5 ARMC7 ATOSB CABP2 CACNB4 CARD9 CCDC102B CCDC120 CCDC13 CCDC57 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CPNE2 CPNE7 CYFIP1 DCLK1 DDX6 DGCR6 DRC7 EDC3 EFHC1 EGLN3 EMD ENKD1 ESRRG EXOC8 EXOSC5 FAM107A FAM124B FAM221B FBXL19 GEM GLYCTK GOLGA1 GPKOW GRB2 GYS1 HDAC4 HGS HNRNPLL INPP5J JAKMIP2 KANK2 KCTD7 KIF9 L3MBTL2 LMNB2 LMO2 LNX1 LONRF1 MAGOHB MAPK9 MID2 MISP MTCL2 MYLIP MYO5B NCDN NCK2 NDOR1 NEK6 NFKBID NME7 NR3C1 PBLD PHF1 PIBF1 PICK1 PLOD3 POLR1C PRPF18 PTK6 QARS1 RAD51D RCOR3 RECK RHOBTB3 RUNX1T1 SNRNP25 SPATA18 SPG21 STK16 TBC1D1 TBC1D22B TEKT4 TRIM42 TRIM50 TSSK3 TUBGCP4 TXK U2AF1 USP2 ZBTB16 ZFHX3 ZZZ3
Entrez ID		102724594	80258
HPRD ID			06540
Ensembl ID		ENSG00000275895	ENSG00000183690
Uniprot IDs			Q5JST6
PDB IDs			2Z13 2Z14 7UNG 8J07
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing RNA Splicing MRNA Metabolic Process MRNA Processing MRNA Binding Regulation Of MRNA Metabolic Process Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome Clathrin Adaptor Complex RNA Processing Nucleic Acid Binding Pre-mRNA Binding RNA Metabolic Process Nucleic Acid Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome RNA Binding Negative Regulation Of RNA Splicing Membrane Coat Clathrin Binding Condensed Chromosome Positive Regulation Of RNA Splicing Somatic Cell DNA Recombination Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Carnosine N-methyltransferase Activity Nucleobase-containing Compound Metabolic Process Protein Domain Specific Binding Cornified Envelope Structural Constituent Of Skin Epidermis Double-strand Break Repair Via Nonhomologous End Joining Non-sequence-specific DNA Binding, Bending Keratinization Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Protein-RNA Sequence-specific Adaptor Activity Poly-pyrimidine Tract Binding Carnosine Metabolic Process Intermediate Filament Organization Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Male Meiosis Chromosome Segregation MutLalpha Complex Keratin Filament Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization	Cytoplasm Protein Binding Protein Phosphorylation Cytoskeleton Regulation Of Podosome Assembly Phosphorylation Centrosome
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