- and KRT75

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		-	KRT75
Description		U2 small nuclear RNA auxiliary factor 1 like 5	keratin 75
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cornified Envelope Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function		Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process		Hematopoietic Progenitor Cell Differentiation Keratinization Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases			Pseudofolliculitis barbae
GWAS		HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		16 interacting genes: AP1B1 AP2B1 CARNMT1 EFHC2 HMGB2 HNRNPK KRT1 KRT75 MEOX2 MLH1 SNRNP35 SRRM4 SRSF3 TRA2B U2AF2 ZNF417	119 interacting genes: - ABI2 AIRIM AMOT ANKS1A ARMC7 ASB15 BCAS2 BEX2 C19orf25 C1orf216 CAMK2A CARD10 CARD9 CATSPERT CCDC102B CCDC197 CCHCR1 CDC37 CDK18 CDKN2D CEP57 CFAP206 CPNE7 CRACR2A DHX15 DMAP1 DTNBP1 DYDC1 EFHC1 EPM2AIP1 FBXO17 FKBP6 GLYCTK GMCL1 GOLGA2 GOLGA6L9 GPANK1 HGS HNRNPF INCA1 IQUB KANK2 KCTD7 KIF9 KIFC3 KRT13 KRT20 KRT24 KRT25 KRT26 KRT27 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 KRT76 LCA5L LMO1 LMO2 LMO4 LONRF1 MAGOHB MID2 MKRN3 MNS1 MTUS2 MYO15B MYOZ3 NCDN NDC80 NEK6 NFKBID NME7 NUDT21 NUP62 OIP5 OSGIN1 PLEKHG4 PM20D2 POLR1C POLR3C RCOR3 RSPH14 SCNM1 SMARCD1 SPAG5 SPTA1 STX11 SUFU TBC1D1 TCHP TEKT1 TEKT4 TJAP1 TNPO2 TNPO3 TRAF1 TRIM23 TRIM27 TRIM54 TRIML2 TSG101 TSSK3 TXLNA TXLNB U2AF1 USHBP1 WASHC1 WASHC3 WWOX XPOT ZNF76 ZWINT
Entrez ID		102724594	9119
HPRD ID			11057
Ensembl ID		ENSG00000275895	ENSG00000170454
Uniprot IDs			O95678
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing RNA Splicing MRNA Metabolic Process MRNA Processing MRNA Binding Regulation Of MRNA Metabolic Process Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome Clathrin Adaptor Complex RNA Processing Nucleic Acid Binding Pre-mRNA Binding RNA Metabolic Process Nucleic Acid Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome RNA Binding Negative Regulation Of RNA Splicing Membrane Coat Clathrin Binding Condensed Chromosome Positive Regulation Of RNA Splicing Somatic Cell DNA Recombination Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Carnosine N-methyltransferase Activity Nucleobase-containing Compound Metabolic Process Protein Domain Specific Binding Cornified Envelope Structural Constituent Of Skin Epidermis Double-strand Break Repair Via Nonhomologous End Joining Non-sequence-specific DNA Binding, Bending Keratinization Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Protein-RNA Sequence-specific Adaptor Activity Poly-pyrimidine Tract Binding Carnosine Metabolic Process Intermediate Filament Organization Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Male Meiosis Chromosome Segregation MutLalpha Complex Keratin Filament Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Keratin Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Structural Molecule Activity Supramolecular Fiber Organization Cytoskeleton Organization Protein Binding Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Motile Cilium Organelle Organization Axonemal A Tubule Inner Sheath Radial Spoke Microtubule-based Process Sperm Flagellum Axonemal Microtubule Cytoplasm Microtubule-based Movement Flagellated Sperm Motility Sperm Motility Cytosol Cilium-dependent Cell Motility Cilium Movement Cilium Movement Involved In Cell Motility Cilium Identical Protein Binding Microtubule Binding Regulation Of Actin Nucleation Microtubule Regulation Of Organelle Organization Spliceosomal Complex CBM Complex Centrosome Regulation Of Arp2/3 Complex-mediated Actin Nucleation Phosphatidylinositol 3-kinase Inhibitor Activity Polymeric Cytoskeletal Fiber Spindle Organization
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