CDK7 and CDK6

  • Number of citations of the paper that reports this interaction (PMID 7629134)
  • 44
  • Data Source:
  • BioGRID (enzymatic study)

CDK7

CDK6

Gene Name cyclin-dependent kinase 7 cyclin-dependent kinase 6
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 47 interactors: APP AR BRCA1 CCNA2 CCNB1 CCNH CDC37 CDK1 CDK2 CDK6 CDK9 CTD CTDP1 CUX1 E2F1 ERCC2 ERCC3 ESR1 GTF2E1 GTF2E2 GTF2H1 GTF2H2 GTF2H3 GTF2H5 HIST1H1A HLA-DQA1 HSD17B4 LASP1 MBP MCM7 MNAT1 NEK6 PCGF6 POLR2A POLR2B PRKCI RARA SMAD1 SRPK1 SRPK2 SUPT5H TAF7 TCEA1 THRA TP53 UBE2D1 VDR 92 interactors: ABI2 ANKRD12 AR ATF6B ATXN1 BCL11A CASC3 CBY1 CCND1 CCND3 CDC37 CDC6 CDK7 CDKN1A CDKN2A CDKN2B CDKN2C CDKN2D CLASRP CNOT7 CTNNB1 DAB1 DDIT3 DEDD2 EBF4 EIF4ENIF1 ELK1 EZH2 FOXM1 FOXO3 HIST1H1A HSF1 ISL1 KIF26B KLF10 LPIN1 MCM10 MCM2 MEF2D MLLT3 MSL3 MYC MZF1 N4BP1 NFATC3 NIPBL NUMA1 PCNA PML POGZ PPARGC1A PPHLN1 PPM1B PPP2CA PRX PSMA3 RB1 RBL1 RBL2 RBM23 RUNX1 SENP3 SIRT1 SLBP SNIP1 SORBS1 SOX10 SOX5 SRSF1 SRSF11 SRSF12 SRSF2 SRSF7 SSBP2 SYNPO2 TCEB3B TFDP1 TGFBR1 TJP2 TPX2 TRA2A TRA2B TRAK1 UHRF2 VGLL4 ZEB1 ZFP36 ZMYM3 ZNF101 ZNF174 ZNF335 ZSCAN1
Entrez ID 1022 1021
HPRD ID 15993 04533
Ensembl ID ENSG00000134058 ENSG00000105810
Uniprot IDs P50613 A4D1G0 Q00534
PDB IDs 1LG3 1PA8 1UA2 2HIC 1BI7 1BI8 1BLX 1G3N 1JOW 1XO2 2EUF 2F2C 3NUP 3NUX 4AUA 4EZ5
Enriched GO Terms of Interacting Partners?
Tagcloud ?
arrested  asynchronous  biochemically  carboxy  cdc2  cip1  enter  extracts  inactivated  machinery  microtubule  mitosis  mitotic  nocodazole  p21waf1  p36  p62  polymerase  polymerization  prepared  reconstituted  repressed  repression  reproduced  rescue  sdi1  shutdown  tfiid  tfiih 
a134c  abp  allelic  ankyrin  balb  cdkn2a  cdkn2b  cdkn2c  cdnas  chr  congenic  d2  dba  g232a  ifna  inbred  inefficient  ink4c  le  multigenic  mus  p15  p16  p18  pctr1  plasmacytoma  pristane  spretus  typed 
Tagcloud (Difference) ?
arrested  asynchronous  biochemically  carboxy  cdc2  cip1  enter  extracts  inactivated  machinery  microtubule  mitosis  mitotic  nocodazole  p21waf1  p36  p62  polymerase  polymerization  prepared  reconstituted  repressed  repression  reproduced  rescue  sdi1  shutdown  tfiid  tfiih 
a134c  abp  allelic  ankyrin  balb  cdkn2a  cdkn2b  cdkn2c  cdnas  chr  congenic  d2  dba  g232a  ifna  inbred  inefficient  ink4c  le  multigenic  mus  p15  p16  p18  pctr1  plasmacytoma  pristane  spretus  typed 
Tagcloud (Intersection) ?