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MAPK12
Gene Name
mitogen-activated protein kinase 12
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Molecular Function
Magnesium Ion Binding
Protein Serine/threonine Kinase Activity
MAP Kinase Activity
Protein Binding
ATP Binding
Biological Process
MAPK Cascade
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
DNA Damage Induced Protein Phosphorylation
Organelle Organization
Mitochondrion Organization
Cell Cycle Arrest
Signal Transduction
Ras Protein Signal Transduction
Muscle Organ Development
Positive Regulation Of Peptidase Activity
Peptidyl-serine Phosphorylation
Muscle Cell Differentiation
Myoblast Differentiation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Muscle Cell Differentiation
Pathways
Signalling to ERKs
Signalling by NGF
Organelle biogenesis and maintenance
CDO in myogenesis
NGF signalling via TRKA from the plasma membrane
VEGFA-VEGFR2 Pathway
Mitochondrial biogenesis
DSCAM interactions
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Myogenesis
Signaling by VEGF
NOD1/2 Signaling Pathway
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
p38MAPK events
Signalling to RAS
Innate Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions
25 interactors:
DLG1
DLG2
DLG3
DLG4
DUSP1
EEF2K
ERBB2IP
GRB2
GTF2I
HTRA2
INADL
MAP2K3
MAP2K4
MAP2K6
MAPKAPK5
MAPT
MBP
PKN1
RGS3
SH3BP5
SIAH1
SNTA1
SNTB1
SRPK1
TERF1
Entrez ID
6300
HPRD ID
03868
Ensembl ID
ENSG00000188130
Uniprot IDs
B7Z274
P53778
PDB IDs
1CM8
Enriched GO Terms of Interacting Partners
?
Receptor Localization To Synapse
Regulation Of Phosphorus Metabolic Process
Protein Localization To Synapse
Regulation Of Catalytic Activity
Regulation Of MAP Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Establishment Or Maintenance Of Apical/basal Cell Polarity
Regulation Of Phosphorylation
Regulation Of Protein Kinase Activity
Signaling
Regulation Of Intracellular Signal Transduction
Regulation Of Protein Phosphorylation
Regulation Of Kinase Activity
Regulation Of Protein Metabolic Process
Cell Communication
Regulation Of Metabolic Process
Regulation Of MAPK Cascade
Muscle System Process
Receptor Clustering
Activation Of Protein Kinase Activity
Activation Of MAPK Activity
Nucleotide Phosphorylation
Response To Stimulus
Regulation Of Cellular Process
Phosphorylation
Intracellular Signal Transduction
Signal Transduction
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Positive Regulation Of MAP Kinase Activity
Muscle Contraction
Cellular Response To Sorbitol
MAPK Cascade
Positive Regulation Of Protein Polymerization
Positive Regulation Of Protein Kinase Activity
Regulation Of Signal Transduction
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of Kinase Activity
Positive Regulation Of Protein Serine/threonine Kinase Activity
Signal Transduction By Phosphorylation
Phosphate-containing Compound Metabolic Process
Positive Regulation Of Catalytic Activity
Axonogenesis
Positive Regulation Of Transferase Activity
Regulation Of Signaling
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Positive Regulation Of Apoptotic Process
Tagcloud
?
6j
acpp
canonical
carcinogenic
cdk5
delineate
e2f6
elf1
glands
gprc5a
hindered
ingenuity
ionizing
ipa
map2
mapped
microarray
nab2
persistently
perturbed
plcg1
ppp4c
radiation
runx1
scarcity
sema4d
stathmin1
surgically
undertook