RNF130

Description		ring finger protein 130
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Programmed Cell Death Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		LDL cholesterol ( 21347282) Pre-treatment viral load in HIV-1 infection ( 31219150) Systolic blood pressure ( 30224653)
Interacting Genes		14 interacting genes: ARPC4 EGFR FGFR3 PDCD1 SCN2A TGFBR1 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2Z
Entrez ID		55819
HPRD ID		11504
Ensembl ID		ENSG00000113269
Uniprot IDs		E5RI87 Q2HIY3 Q86XS8
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein K48-linked Ubiquitination ATP Binding Ubiquitin-protein Transferase Activity Protein Polyubiquitination Nucleotide Binding Transferase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Monoubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Protein Modification Process Protein K11-linked Ubiquitination Macromolecule Catabolic Process Proteolysis Protein K63-linked Ubiquitination Apoptotic Process Cell Death Programmed Cell Death Positive Regulation Of Protein Polyubiquitination Protein Metabolic Process Regulation Of Protein Modification Process Positive Regulation Of Protein Modification Process Protein K6-linked Ubiquitination Regulation Of Protein Polyubiquitination Catabolic Process Receptor Complex Regulation Of Protein Ubiquitination Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Activity Multivesicular Body, Internal Vesicle Lumen Regulatory T Cell Apoptotic Process Negative Regulation Of Tolerance Induction Regulation Of Post-translational Protein Modification TORC1 Signaling Negative Regulation Of TORC1 Signaling Negative Regulation Of BMP Signaling Pathway Shc-EGFR Complex Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Vascular Endothelial Cell Proliferation Epicardium Morphogenesis Protein Autoubiquitination Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Ubiquitin Protein Ligase Binding Regulation Of Peptidyl-tyrosine Phosphorylation Intracellular Signal Transduction
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