MAGEA3 and KIF27

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAGEA3	KIF27
Description		MAGE family member A3	kinesin family member 27
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum	Extracellular Region Cytoplasm Cytoskeleton Kinesin Complex Microtubule Cilium Cell Projection
	Molecular Function	Protein Binding Histone Deacetylase Binding Caspase Binding	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Autophagy Negative Regulation Of Protein Processing Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Microtubule-based Movement Ventricular System Development Cell Projection Organization Establishment Of Localization In Cell Cilium Assembly
Pathways			COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS			Eosinophil percentage of white cells ( 32888494) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Multiple sclerosis ( 31604244) Reaction time ( 29844566) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		15 interacting genes: ACOT7 BCL7B CINP DNM1L ENOX2 EXOC5 HLA-DRB1 HTT IQSEC1 KIF27 LSM2 PCYT1A PRKAA1 RUSC1 S100A9	3 interacting genes: FOXP1 MAGEA3 MAGEA6
Entrez ID		4102	55582
HPRD ID		02166	11179
Ensembl ID		ENSG00000221867	ENSG00000165115
Uniprot IDs		P43357	Q86VH2
PDB IDs		1QEW 4V0P 5BRZ 8T9A 9BD2
Enriched GO Terms of Interacting Partners?		Cell Death Programmed Cell Death Positive Regulation Of Immune Response To Tumor Cell Regulation Of T Cell Mediated Immune Response To Tumor Cell Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Phosphatidylcholine Biosynthetic Process Regulation Of Response To Tumor Cell	Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Autophagy Histone Deacetylase Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Interleukin-21 Production Negative Regulation Of Programmed Cell Death Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Regulation Of RNA Metabolic Process Osteoclast Development Regulation Of Macrophage Colony-stimulating Factor Production Regulation Of Endothelial Tube Morphogenesis Positive Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cell Communication Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Negative Regulation Of Signaling Monocyte Activation Endothelial Cell Activation T Follicular Helper Cell Differentiation Caspase Binding Regulation Of Autophagy Negative Regulation Of Catabolic Process Beta-catenin-TCF Complex Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of B Cell Apoptotic Process Striatum Development Regulation Of Defense Response To Bacterium Negative Regulation Of Androgen Receptor Signaling Pathway Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Regulation Of Monocyte Differentiation Core Promoter Sequence-specific DNA Binding Negative Regulation Of Anoikis Regulation Of B Cell Apoptotic Process Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Protein Processing Regulation Of Intracellular Signal Transduction
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