MAGEA3 and BCL7B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAGEA3	BCL7B
Description		MAGE family member A3	BAF chromatin remodeling complex subunit BCL7B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum	Chromatin Nucleoplasm SWI/SNF Complex GBAF Complex
	Molecular Function	Protein Binding Histone Deacetylase Binding Caspase Binding	Actin Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Autophagy Negative Regulation Of Protein Processing Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Apoptotic Process Positive Regulation Of Cell Population Proliferation Wnt Signaling Pathway Regulation Of Mitotic Metaphase/anaphase Transition Cell Differentiation Negative Regulation Of Cell Differentiation Regulation Of G0 To G1 Transition Positive Regulation Of Stem Cell Population Maintenance Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Double-strand Break Repair Regulation Of Nucleotide-excision Repair
Pathways			Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the canonical BAF (cBAF) complex Formation of the polybromo-BAF (pBAF) complex Formation of the embryonic stem cell BAF (esBAF) complex Formation of the non-canonical BAF (ncBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Diseases
GWAS			C-reactive protein levels ( 21300955 30388399) Diastolic blood pressure ( 27841878) Hypertriglyceridemia ( 23505323) Lamb consumption ( 32066663) Liver enzyme levels (alkaline phosphatase) ( 33972514) Malaria ( 31844061) Meat-related diet ( 32066663) Non-oily fish consumption ( 32066663) Red cell distribution width ( 32888494) Triglycerides ( 18193044 20864672) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		15 interacting genes: ACOT7 BCL7B CINP DNM1L ENOX2 EXOC5 HLA-DRB1 HTT IQSEC1 KIF27 LSM2 PCYT1A PRKAA1 RUSC1 S100A9	4 interacting genes: MAGEA3 MAGEA6 TERF1 TERF2IP
Entrez ID		4102	9275
HPRD ID		02166	05786
Ensembl ID		ENSG00000221867	ENSG00000106635
Uniprot IDs		P43357	F2Z3H6 Q9BQE9
PDB IDs		1QEW 4V0P 5BRZ 8T9A 9BD2
Enriched GO Terms of Interacting Partners?		Cell Death Programmed Cell Death Positive Regulation Of Immune Response To Tumor Cell Regulation Of T Cell Mediated Immune Response To Tumor Cell Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Phosphatidylcholine Biosynthetic Process Regulation Of Response To Tumor Cell	Nuclear Telomere Cap Complex Shelterin Complex G-rich Strand Telomeric DNA Binding Telomere Capping Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Telomeric DNA Binding Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Telomere Maintenance DNA Biosynthetic Process Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Negative Regulation Of Chromosome Organization Positive Regulation Of Shelterin Complex Assembly Telomere Maintenance Negative Regulation Of Autophagy Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Histone Deacetylase Binding Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomere Organization Negative Regulation Of DNA Recombination At Telomere Negative Regulation Of DNA Metabolic Process Chromosome, Telomeric Region T Cell Antigen Processing And Presentation Membrane To Membrane Docking T Cell Extravasation Negative Regulation Of Apoptotic Signaling Pathway Receptor-mediated Virion Attachment To Host Cell Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Telomerase Activity Regulation Of Chromosome Organization Ankyrin Repeat Binding Protection From Non-homologous End Joining At Telomere Negative Regulation Of Macromolecule Metabolic Process T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Positive Regulation Of DNA Metabolic Process Telomere Localization Telomeric D-loop Disassembly Double-stranded Telomeric DNA Binding Negative Regulation Of Metabolic Process Virion Attachment To Host Cell Telomeric Loop Disassembly
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