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PPARD and KRTAP10-7
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
PPARD
KRTAP10-7
Gene Name
peroxisome proliferator-activated receptor delta
keratin associated protein 10-7
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Keratin Filament
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Steroid Hormone Receptor Activity
Transcription Coactivator Activity
Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Protein Binding
Drug Binding
Zinc Ion Binding
Lipid Binding
Sequence-specific DNA Binding
NF-kappaB Binding
Linoleic Acid Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Glucose Metabolic Process
Proteoglycan Metabolic Process
Generation Of Precursor Metabolites And Energy
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Lipid Metabolic Process
Fatty Acid Beta-oxidation
Vitamin A Metabolic Process
Heart Development
Embryo Implantation
Cholesterol Metabolic Process
Cell Proliferation
Positive Regulation Of Cell Proliferation
Axon Ensheathment
Phospholipid Biosynthetic Process
Fatty Acid Catabolic Process
MRNA Transcription
Response To Glucose
Gene Expression
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Response To Activity
Negative Regulation Of Smooth Muscle Cell Migration
Glucose Transport
Fatty Acid Transport
Cell Differentiation
Negative Regulation Of Cell Growth
Intracellular Receptor Signaling Pathway
Cell-substrate Adhesion
Positive Regulation Of Insulin Secretion
Negative Regulation Of Collagen Biosynthetic Process
Response To Vitamin A
Wound Healing
Negative Regulation Of Apoptotic Process
Steroid Hormone Mediated Signaling Pathway
Keratinocyte Proliferation
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Epidermis Development
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Vasodilation
Decidualization
Negative Regulation Of Smooth Muscle Cell Proliferation
Negative Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Inflammatory Response
Keratinocyte Migration
Adipose Tissue Development
Cellular Response To Hypoxia
Apoptotic Signaling Pathway
Pathways
Regulation of pyruvate dehydrogenase (PDH) complex
Pyruvate metabolism
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Signaling by Retinoic Acid
Import of palmitoyl-CoA into the mitochondrial matrix
Pyruvate metabolism and Citric Acid (TCA) cycle
Nuclear Receptor transcription pathway
The citric acid (TCA) cycle and respiratory electron transport
Drugs
Icosapent
Treprostinil
Sulindac
Bezafibrate
Heptyl-Beta-D-Glucopyranoside
(11E)-OCTADEC-11-ENOIC ACID
(2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid
2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid
3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid
{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid
Diseases
GWAS
Cataracts in type 2 diabetes (
23137000
)
Height (
21998595
)
Pulmonary function (interaction) (
23284291
)
Response to antipsychotic treatment (
20195266
)
Protein-Protein Interactions
39 interactors:
BCL6
CEP350
DUT
EIF3I
EP300
GADD45B
GADD45G
GLUL
HDAC1
HDAC2
HDAC3
HDAC4
HDAC7
HSP90AA1
ITGB5
KDM1A
KRTAP10-3
KRTAP10-7
NCOA1
NCOA2
NCOA3
NCOR1
NCOR2
NR0B2
NRIP1
PEBP1
PPARGC1A
PRDX6
PRMT3
PROX1
RANBP9
RXRA
RXRB
RXRG
SHMT2
SMAD9
SPEN
SRC
TNP1
215 interactors:
AEN
AES
ALDH3B1
ANKRD36BP1
AP1M1
APP
AQP1
AVPI1
B4GALT7
BAHD1
BCL6B
BMP7
BUD31
BYSL
C16orf59
C19orf57
C19orf66
C8orf33
C9orf9
CARHSP1
CARKD
CATIP
CBX2
CCDC185
CCDC26
CCNG1
CDCA7L
CHIC2
CHRD
CHRNG
CLK1
CLK4
COL8A1
CRCT1
CREB5
CSNK1G1
CSNK1G2
CTNNBIP1
CTRC
CXCL16
DAAM2
DERL2
DHX57
DMRT3
E2F6
E4F1
EHHADH
FAM124B
FAM161A
FAM27E3
FAM74A4
FAM76B
FARS2
GABARAPL1
GABARAPL2
GEM
GLIDR
GLP1R
GNE
GOLGA8EP
GRN
GSTP1
GUCD1
HBZ
HHEX
HPCAL1
HSBP1
HSD3B7
IGSF8
ING5
INPP5D
IQUB
KLHL38
KRT20
KRT83
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP4-2
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE1B
LCE2A
LCE3E
LCE4A
LIMS2
LINC00242
LMNA
LMO2
LRCH4
MAPKBP1
MCM5
MOBP
MRGBP
MXD3
MXI1
NAA10
NOL12
NOTCH2NL
NPBWR2
NPDC1
NUBP2
NUDCD3
NUFIP2
P2RY6
PCED1A
PCSK5
PDIA5
PDLIM5
PFKL
PIN1
POLL
POM121L8P
PPARD
PRKAB2
PRM2
PRR13
PTGDS
PTGER3
PTPMT1
PVR
PVRL2
PVRL3
RNF175
RPF1
RPL11
RPL36AL
RPS28
RPUSD3
RSPO2
RTN4RL1
RWDD2B
SCNM1
SDCBP
SLC23A1
SLC25A48
SLC6A20
SMCO4
SMCP
SPATA3
SPATA8
SPG7
SPRY1
SSX2IP
STK16
SUV39H1
TAPBPL
TCEA2
TCEANC
THAP1
THAP6
TMA16
TMEM8A
TNP2
TNS2
TOR1A
TREX1
TRIM42
TULP3
TXNDC5
TYRO3
UCP2
UXT
VTI1B
WDYHV1
WNT11
ZBTB24
ZBTB38
ZBTB9
ZFYVE26
ZNF101
ZNF124
ZNF133
ZNF155
ZNF165
ZNF169
ZNF175
ZNF180
ZNF2
ZNF20
ZNF223
ZNF250
ZNF26
ZNF266
ZNF32
ZNF320
ZNF329
ZNF337
ZNF41
ZNF417
ZNF418
ZNF419
ZNF425
ZNF433
ZNF439
ZNF490
ZNF543
ZNF555
ZNF564
ZNF572
ZNF578
ZNF581
ZNF587
ZNF625
ZNF670
ZNF697
ZNF707
ZNF778
ZNF792
ZNF846
ZNHIT1
ZSCAN26
Entrez ID
5467
386675
HPRD ID
02679
11193
Ensembl ID
ENSG00000112033
ENSG00000205441
Uniprot IDs
F1D8S7
Q03181
P60409
PDB IDs
1GWX
1Y0S
2AWH
2B50
2BAW
2ENV
2GWX
2J14
2Q5G
2XYJ
2XYW
2XYX
2ZNP
2ZNQ
3D5F
3DY6
3ET2
3GWX
3GZ9
3OZ0
3PEQ
3SP9
3TKM
Enriched GO Terms of Interacting Partners
?
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Transcription, DNA-templated
Negative Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
RNA Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Rhythmic Process
Chromatin Organization
Positive Regulation Of Macromolecule Biosynthetic Process
Chromatin Modification
Positive Regulation Of Metabolic Process
Circadian Rhythm
Response To Organic Substance
Histone Modification
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Macromolecule Biosynthetic Process
Intracellular Receptor Signaling Pathway
Circadian Regulation Of Gene Expression
Gene Expression
Regulation Of Transcription, DNA-templated
Histone H4 Deacetylation
Multicellular Organismal Development
Cellular Response To Organic Substance
Organelle Organization
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Biosynthetic Process
RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Chromosome Organization
Developmental Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Cell Differentiation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Metabolic Process
Histone H3 Deacetylation
RNA Biosynthetic Process
Transcription, DNA-templated
RNA Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Cellular Metabolic Process
Cellular Process
Regulation Of Metabolic Process
Regulation Of Cellular Process
Susceptibility To T Cell Mediated Cytotoxicity
Transepithelial Transport
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Metabolic Process
Keratinization
Susceptibility To Natural Killer Cell Mediated Cytotoxicity
Developmental Process
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning
Negative Regulation Of Mesenchymal Cell Proliferation
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Negative Regulation Of Gene Expression
Cellular Response To Oxygen Levels
Cellular Response To Topologically Incorrect Protein
Cellular Response To Stress
Penetration Of Zona Pellucida
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Spinal Cord Dorsal/ventral Patterning
Positive Regulation Of Immune Response To Tumor Cell
Multicellular Organismal Development
Spinal Cord Patterning
Negative Regulation Of Cellular Metabolic Process
Respiratory Tube Development
Tagcloud
?
almendro
birc5
casein
catenin
cd44
deregulate
distinguished
dvl1
ffpe
fzd7
gonen
ly294002
martins
mimicking
mmp7
modulators
notch1
pam50
park
pten
readout
subpopulation
sulfide
sulindac
tnbc
wp
xav939
zymograph
Tagcloud (Difference)
?
almendro
birc5
casein
catenin
cd44
deregulate
distinguished
dvl1
ffpe
fzd7
gonen
ly294002
martins
mimicking
mmp7
modulators
notch1
pam50
park
pten
readout
subpopulation
sulfide
sulindac
tnbc
wp
xav939
zymograph
Tagcloud (Intersection)
?