TMEM239 and FXYD6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM239	FXYD6
Description		transmembrane protein 239	FXYD domain containing ion transport regulator 6
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Plasma Membrane Membrane Presynaptic Membrane Postsynaptic Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Binding Sodium Channel Regulator Activity Ion Channel Regulator Activity
	Biological Process		Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Regulation Of Monoatomic Ion Transport Positive Regulation Of Sodium Ion Export Across Plasma Membrane
Pathways			Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31451708) Pulse pressure ( 30224653) White matter integrity ( 23218918)	Hippocampal volume in Alzheimer's disease dementia ( 29274321) Myopia ( 27182965)
Interacting Genes		68 interacting genes: AQP6 ATF7 CD79A CLDN20 CLRN1 COQ8A CREB3L1 CREB3L3 CXCL16 DARS2 DCUN1D1 EBP EMP1 FAM174A FAM209A FBXL19 FFAR2 FGD2 FKBP7 FTHL17 FXYD6 GJA8 GPR101 GPR151 GPR42 LENG1 LNX1 MIEF2 MPP1 MS4A3 MTIF3 MTURN MYG1 NTAQ1 OCIAD1 ODF4 OTULIN PDCD1LG2 PNKP POLI PSCA REEP2 RETREG3 S100B SCAND1 SCN3B SDCBP SENP2 SERINC2 SLC10A1 SLC10A6 SLC18A1 SLC34A2 SLC35H1 SLC71A2 SNX1 SNX2 SPG21 SSMEM1 SYT16 TBRG4 TIMMDC1 TMEM248 TMEM31 TMX2 TRHR UBASH3A USP5	67 interacting genes: APCDD1L APH1A AQP6 ARL13B BCAR1 C4BPA CCDC90B CD74 CERS4 CLDN7 CLEC10A CREB3 CREB3L1 DERL2 EBP ELOVL2 ELOVL4 ERGIC3 FAM209A FCER1G FFAR2 FPR2 GDF9 GJA8 GPR42 HAUS2 JAGN1 KCNJ6 LHFPL2 LHFPL5 LMNA MFF MGST3 MMGT1 OCIAD1 PEX12 PGRMC2 PPP1CC RBM48 RHBDL1 RHCG RNASEK SCN3B SLC10A1 SLC10A6 SLC16A7 SLC30A2 SLC35E1 SLC35E3 SLC35H1 SLC39A2 SLC47A1 SVOP TLCD4 TLE1 TM4SF18 TMEM154 TMEM237 TMEM239 TMEM31 TMEM35A TMEM72 TMEM86B TMPPE TP53 TRIM27 UNC119
Entrez ID		100288797	53826
HPRD ID			09456
Ensembl ID		ENSG00000198326	ENSG00000137726
Uniprot IDs		Q8WW34	Q9H0Q3
PDB IDs			8D3U 8D3V 8D3W 8D3X 8D3Y
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Retromer, Tubulation Complex Leptin Receptor Binding Bile Acid:sodium Symporter Activity	Membrane Transmembrane Transport Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum Antiporter Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Bile Acid:sodium Symporter Activity Monoatomic Ion Transport Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid
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