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TMEM239 and SENP2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
TMEM239
SENP2
Gene Name
transmembrane protein 239
SUMO1/sentrin/SMT3 specific peptidase 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Integral Component Of Membrane
Nuclear Pore
Nucleoplasm
PML Body
Cytoplasmic Vesicle
Nuclear Membrane
Molecular Function
Protein Binding
SUMO-specific Protease Activity
Protein Domain Specific Binding
Biological Process
Positive Regulation Of Protein Phosphorylation
Proteolysis
Heart Development
Dorsal/ventral Axis Specification
Protein Transport
Wnt Signaling Pathway
Protein Sumoylation
Protein Desumoylation
Regulation Of Wnt Signaling Pathway
Negative Regulation Of Protein Binding
Regulation Of DNA Endoreduplication
Negative Regulation Of Chromatin Binding
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Post-translational Protein Modification
Cellular Protein Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
MRNA Transport
Trophoblast Giant Cell Differentiation
Labyrinthine Layer Development
Spongiotrophoblast Layer Development
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
SUMO is proteolytically processed
Post-translational protein modification
SUMOylation
Processing and activation of SUMO
Drugs
Diseases
GWAS
White matter integrity (
23218918
)
Protein-Protein Interactions
11 interactors:
ADCK3
ATF7
C12orf10
CXCL16
FGD2
LENG1
POLI
SDCBP
SENP2
USP5
WDYHV1
21 interactors:
AGTRAP
APP
ARL6IP1
AXIN1
CCDC155
CDCA5
CDK5RAP2
DAXX
FUNDC1
IKBKG
NEDD4L
NUP153
PML
RANGAP1
SUMO1
SUMO2
SUMO3
SYNE4
TMEM239
TPD52
TRIM63
Entrez ID
100288797
59343
HPRD ID
07002
Ensembl ID
ENSG00000198326
Uniprot IDs
Q6ZU23
Q8WW34
Q9HC62
PDB IDs
1TGZ
1TH0
2IO0
2IO1
2IO2
2IO3
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Proteolysis
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Catabolic Process
Cellular Localization
Positive Regulation Of Protein Catabolic Process
Protein Sumoylation
Positive Regulation Of Cellular Protein Metabolic Process
PML Body Organization
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Protein Modification By Small Protein Conjugation
Regulation Of Proteolysis
Establishment Of Localization In Cell
Intracellular Receptor Signaling Pathway
Regulation Of Protein Ubiquitination
Positive Regulation Of Metabolic Process
Mitotic Cell Cycle
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Response To Stress
Regulation Of Protein Metabolic Process
Positive Regulation Of Proteasomal Protein Catabolic Process
JNK Cascade
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Cell Cycle
Viral Process
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Stress-activated MAPK Cascade
Establishment Of Organelle Localization
Stress-activated Protein Kinase Signaling Cascade
Nucleus Organization
Cell Cycle Process
Regulation Of Cellular Localization
Cellular Response To Stress
Mitotic Cell Cycle Process
Response To Abiotic Stimulus
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Activation Of MAPK Activity
Organelle Localization
Protein Localization To Nucleus
Regulation Of Protein Localization
Endoplasmic Reticulum Calcium Ion Homeostasis
Regulation Of Intracellular Transport
Cell Surface Receptor Signaling Pathway
Organelle Organization
Activation Of JUN Kinase Activity
Cellular Response To Stimulus
Cellular Response To DNA Damage Stimulus
Establishment Of Chromosome Localization
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Tagcloud
?
adequate
aerobic
atp
consistently
displaying
exhibit
glucose
glycolysis
glycolytic
hif1alpha
knockout
lactate
ly294002
mcf7
mef
mefs
metabolism
protease
proteases
represses
rescued
respiration
reveals
senps
shifts
subcellular
sumo
sumoylate
supply
Tagcloud (Difference)
?
adequate
aerobic
atp
consistently
displaying
exhibit
glucose
glycolysis
glycolytic
hif1alpha
knockout
lactate
ly294002
mcf7
mef
mefs
metabolism
protease
proteases
represses
rescued
respiration
reveals
senps
shifts
subcellular
sumo
sumoylate
supply
Tagcloud (Intersection)
?