BCL2L10 and MGST2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BCL2L10	MGST2
Description		BCL2 like 10	microsomal glutathione S-transferase 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Spindle Cytosol Cytoskeleton Membrane Nuclear Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Calcium Ion Binding Protein Binding Channel Activity Caspase Binding	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Enzyme Activator Activity Oxidoreductase Activity Transferase Activity Lyase Activity Identical Protein Binding Glutathione Binding
	Biological Process	Release Of Cytochrome C From Mitochondria Apoptotic Process Spermatogenesis Female Gamete Generation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Microtubule Organizing Center Organization Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Transmembrane Transport Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Lipid Metabolic Process Leukotriene Metabolic Process Glutathione Biosynthetic Process Leukotriene Biosynthetic Process Response To Lipopolysaccharide Carboxylic Acid Biosynthetic Process Membrane Lipid Catabolic Process Positive Regulation Of Inflammatory Response Cellular Oxidant Detoxification
Pathways			Glutathione conjugation Aflatoxin activation and detoxification
Drugs			Glutathione
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		14 interacting genes: APAF1 BAD BAK1 BAX BCL2 BCL2L1 BCL2L11 BECN1 BMF CASP8 MGST2 NR4A1 SAMD4B TMEM200A	23 interacting genes: ASIC1 BCL2L10 BCL2L2 C3orf52 CCL3L3 CLEC14A CREB3 CREB3L1 CTXN3 DNAJC30 GIMAP5 GJA8 GPX8 HDHD2 PLN PNKP SEC22A SEC22B SGCB STX8 TMEM167B TMEM207 VAMP3
Entrez ID		10017	4258
HPRD ID		06071	03436
Ensembl ID		ENSG00000137875	ENSG00000085871
Uniprot IDs		H0YMD5 Q9HD36	Q99735
PDB IDs		4B4S	6SSR 6SSS 6SSU 6SSW
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Bcl-2 Family Protein Complex Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Release Of Cytochrome C From Mitochondria Mitochondrial Outer Membrane Extrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Membrane Permeability Apoptotic Process Release Of Cytochrome C From Mitochondria Cell Death Programmed Cell Death Apoptotic Mitochondrial Changes Positive Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Membrane Permeability Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Intrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Mitochondrial Membrane Organization Regulation Of Apoptotic Signaling Pathway Regulation Of Mitochondrion Organization Leukocyte Apoptotic Process Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Regulation Of Mitochondrial Membrane Potential Regulation Of Intrinsic Apoptotic Signaling Pathway B Cell Homeostasis T Cell Apoptotic Process BH3 Domain Binding Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Lymphocyte Apoptotic Process Positive Regulation Of IRE1-mediated Unfolded Protein Response Channel Activity Mitochondrion Organization Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Thymocyte Apoptotic Process Response To Gamma Radiation B Cell Apoptotic Process Positive Regulation Of Apoptotic Signaling Pathway Calcium Ion Transport Into Cytosol Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Pore Complex Regulation Of Developmental Pigmentation Lymphocyte Homeostasis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of IRE1-mediated Unfolded Protein Response Mitochondrial Membrane Reproductive Structure Development Membrane Organization Leukocyte Homeostasis	SNAP Receptor Activity Membrane Membrane Fusion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?