MGST2 and DNAJC30

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MGST2	DNAJC30
Description		microsomal glutathione S-transferase 2	DnaJ heat shock protein family (Hsp40) member C30
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GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Intracellular Membrane-bounded Organelle	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Enzyme Activator Activity Oxidoreductase Activity Transferase Activity Lyase Activity Identical Protein Binding Glutathione Binding	Protein Binding
	Biological Process	Lipid Metabolic Process Leukotriene Metabolic Process Glutathione Biosynthetic Process Leukotriene Biosynthetic Process Response To Lipopolysaccharide Carboxylic Acid Biosynthetic Process Membrane Lipid Catabolic Process Positive Regulation Of Inflammatory Response Cellular Oxidant Detoxification	ATP Biosynthetic Process Brain Development Regulation Of Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways		Glutathione conjugation Aflatoxin activation and detoxification
Drugs		Glutathione
Diseases
GWAS		Metabolite levels ( 23823483)	Malaria ( 31844061)
Interacting Genes		23 interacting genes: ASIC1 BCL2L10 BCL2L2 C3orf52 CCL3L3 CLEC14A CREB3 CREB3L1 CTXN3 DNAJC30 GIMAP5 GJA8 GPX8 HDHD2 PLN PNKP SEC22A SEC22B SGCB STX8 TMEM167B TMEM207 VAMP3	30 interacting genes: AQP6 BEST2 CALN1 CREB3 EBP EXOSC6 FAM209A FATE1 FBXO7 GPX8 JAGN1 KASH5 LMNA LRRC25 MGST2 MRM1 MSMO1 OPRL1 PEX12 REEP4 RNF170 S100B SIGLEC12 SLC10A4 SLC35H1 SLC51A SLC71A2 TMEM31 TMEM52B TMEM86B
Entrez ID		4258	84277
HPRD ID		03436	10303
Ensembl ID		ENSG00000085871	ENSG00000176410
Uniprot IDs		Q99735	B3KSU4 Q96LL9
PDB IDs		6SSR 6SSS 6SSU 6SSW	2YUA
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity Membrane Membrane Fusion	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum
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