BCL2L10 and SAMD4B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BCL2L10	SAMD4B
Description		BCL2 like 10	sterile alpha motif domain containing 4B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Spindle Cytosol Cytoskeleton Membrane Nuclear Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site	P-body Nucleus Cytoplasm Cytosol
	Molecular Function	Calcium Ion Binding Protein Binding Channel Activity Caspase Binding	RNA Binding MRNA Binding Protein Binding Translation Repressor Activity
	Biological Process	Release Of Cytochrome C From Mitochondria Apoptotic Process Spermatogenesis Female Gamete Generation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Microtubule Organizing Center Organization Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Transmembrane Transport Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Translation Regulation Of MRNA Stability
Pathways
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33339817) Obesity-related traits ( 23251661)
Interacting Genes		14 interacting genes: APAF1 BAD BAK1 BAX BCL2 BCL2L1 BCL2L11 BECN1 BMF CASP8 MGST2 NR4A1 SAMD4B TMEM200A	8 interacting genes: BCL2L10 CCDC179 CFTR LRRC8E NUTM1 RSRC2 USP53 YWHAG
Entrez ID		10017	55095
HPRD ID		06071	10960
Ensembl ID		ENSG00000137875	ENSG00000179134
Uniprot IDs		H0YMD5 Q9HD36	M0QZ22 Q5PRF9 Q66K25 Q8IXP7
PDB IDs		4B4S
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Bcl-2 Family Protein Complex Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Release Of Cytochrome C From Mitochondria Mitochondrial Outer Membrane Extrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Membrane Permeability Apoptotic Process Release Of Cytochrome C From Mitochondria Cell Death Programmed Cell Death Apoptotic Mitochondrial Changes Positive Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Membrane Permeability Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Intrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Mitochondrial Membrane Organization Regulation Of Apoptotic Signaling Pathway Regulation Of Mitochondrion Organization Leukocyte Apoptotic Process Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Regulation Of Mitochondrial Membrane Potential Regulation Of Intrinsic Apoptotic Signaling Pathway B Cell Homeostasis T Cell Apoptotic Process BH3 Domain Binding Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Lymphocyte Apoptotic Process Positive Regulation Of IRE1-mediated Unfolded Protein Response Channel Activity Mitochondrion Organization Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Thymocyte Apoptotic Process Response To Gamma Radiation B Cell Apoptotic Process Positive Regulation Of Apoptotic Signaling Pathway Calcium Ion Transport Into Cytosol Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Pore Complex Regulation Of Developmental Pigmentation Lymphocyte Homeostasis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of IRE1-mediated Unfolded Protein Response Mitochondrial Membrane Reproductive Structure Development Membrane Organization Leukocyte Homeostasis
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